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Synthesis 2015; 47(20): 3179-3185
DOI: 10.1055/s-0034-1378850
DOI: 10.1055/s-0034-1378850
paper
Indium(III)-Catalyzed Reduction of Nitrobenzenes to Anilines: Scope and Limitations
Further Information
Publication History
Received: 30 April 2015
Accepted after revision: 18 May 2015
Publication Date:
15 July 2015 (online)
Abstract
We have demonstrated that a combination of indium(III) iodide and 1,1,3,3-tetramethyldisiloxane (TMDS) effectively catalyzes the chemoselective reduction of nitrobenzenes with a variety of functional groups (halogens, alkyl, alkoxy, hydroxy, ester, amino, amide, cyanide, thiol, and an alkene moiety), producing the corresponding aniline derivatives.
Supporting Information
- Supporting information for this article is available online at http://dx.doi.org/10.1055/s-0034-1378850.
- Supporting Information
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