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Thorac Cardiovasc Surg 2011; 59(8): 454-459
DOI: 10.1055/s-0030-1271028
Original Cardiovascular

© Georg Thieme Verlag KG Stuttgart · New York

Long-term Results of Mechanical and Biological Heart Valves in Dialysis and Non-Dialysis Patients

A. Böning1 , R.-H. Boedeker2 , U. P. Rosendahl3 , B. Niemann1 , S. Haberer1 , P. Roth1 , J. A. C. Ennker3
  • 1Department of Cardiovascular Surgery, University Hospital Giessen, Giessen, Germany
  • 2Justus-Liebig-University Giessen, Institute for Medical Statistics, Giessen, Germany
  • 3Mediclin Heart Institute, Lahr, Germany
Further Information

Publication History

received February 4, 2011 revised March 8, 2011

accepted March 10, 2011

Publication Date:
03 May 2011 (online)

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Abstract

Introduction: We wanted to answer the question whether biological heart valves are inferior compared to mechanical heart valves in end-stage renal disease (ESRD) patients. Methods: Between 01/1996 und 12/2006, 44 of 3293 patients undergoing aortic valve replacement (AVR) in a single institution suffered from dialysis-dependent ESRD and underwent a follow-up investigation after 1.9 years (median). Twelve (28.9 %) of these patients received a biological, 32 (71.1 %) of these patients a mechanical aortic valve prosthesis. To evaluate a possible influence of the valve type (biological/mechanical) on survival, uni- and multivariate logistic regression was used. Results: ESRD patients after AVR had a relatively poor short-term (30-day mortality: 22.7 %) and long-term survival (median survival time: 24.7 months; 95 % CI: 0.2–47.7 months), irrespective of the type of heart valve prosthesis (hazard ratio for mortality depending on heart valve type in dialysis patients: 1.31, p = 0.400). Dialysis-dependent patients were not reoperated due to valve-related reasons. Conclusions: The long-term survival of dialysis-dependent patients after AVR is low (5-year survival: 29.5 %) irrespective of the type of heart valve prosthesis. Therefore, the use of biological AVR is not contraindicated in this group of patients.

Key words

kidney (includes related subject matter) - heart valve surgery - cardiac - dialysis - end-stage renal disease - aortic valve replacement - biological aortic valve prosthesis - mechanical aortic valve prosthesis - long-term survival - mortality risk factors

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Prof. Andreas Böning, MD, PHD

Department of Cardiovascular Surgery
University Hospital Giessen

Rudolf-Buchheim-Str. 7

35385 Giessen

Germany

Phone: +49 6 41 98 54 43 00

Fax: +49 6 41 98 54 43 09

Email: andreas.boening@chiru.med.uni-giessen.de

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