Iron-Catalyzed Deprotonative Alkylation of (Hetero)Arenes

L. D. Tran; O. Daugulis

doi:10.1055/s-0030-1259111

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Synfacts 2011(1): 0084-0084
DOI: 10.1055/s-0030-1259111

Metal-Mediated Synthesis

Iron-Catalyzed Deprotonative Alkylation of (Hetero)Arenes

Contributor(s): Paul Knochel, Tobias Thaler
L. D. Tran, O. Daugulis*
University of Houston, USA

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Publication History

Publication Date:
21 December 2010 (online)

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Significance

A new method for the iron-catalyzed deprotonative alkylation of arenes using primary and secondary alkyl halides was developed. A broad range of heterocycles and electron-poor arenes was efficiently alkylated.