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Synfacts 2010(12): 1402-1402  
DOI: 10.1055/s-0030-1258852
Metal-Mediated Synthesis
© Georg Thieme Verlag Stuttgart ˙ New York

Alkenylative Cross-Coupling between Alkyl Sulfides and Grignard Reagents

Contributor(s): Paul Knochel, Tobias Thaler
K. Ishizuka, H. Seike, T. Hatakeyama, M. Nakamura*
Kyoto University, Japan
Further Information

Publication History

Publication Date:
22 November 2010 (online)

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Corrected by:

Alkenylative Cross-Coupling between Alkyl Sulfides and Grignard ReagentsSynfacts 2011; 2011(02): 0236-0236
DOI: 10.1055/s-0030-1259391

Significance

A novel nickel-catalyzed alkenylative coupling between aryl Grignard reagents and alkyl aryl sulfides was developed. The key feature of this reaction is the use of a bulky NHC ligand (SIPr) that suppresses the conventional biaryl coupling reaction.