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Synfacts 2010(10): 1156-1156  
DOI: 10.1055/s-0030-1258685
Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions
© Georg Thieme Verlag Stuttgart ˙ New York

Enantioselective 1,3-Dipolar Cycloadditions of N-Methylnitrones and Enals

Contributor(s): Hisashi Yamamoto, Kimberly Griffin
A. Bădoiu, G. Bernardinelli, E. P. Kündig*
University of Geneva, Switzerland
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Publication History

Publication Date:
22 September 2010 (online)

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Significance

The authors extended their investigation of 1,3-dicycloadditions of nitrones and enals. In this report less reactive N-alkylnitrones were used, which are synthetically more appealing than the diarylnitrones previously used, as chiral amino alcohols and amino acids can be easily ­accessed.