Eur J Pediatr Surg 2010; 20(1): 1-4
DOI: 10.1055/s-0029-1231053
Review

© Georg Thieme Verlag KG Stuttgart · New York

A Review of Venovenous and Venoarterial Extracorporeal Membrane Oxygenation in Neonates and Children

S. J. Keckler1 , C. A. Laituri1 , D. J. Ostlie2 , S. D. St. Peter2
  • 1Children's Mercy Hospital, Department of Surgery, Kansas City, United States
  • 2Children's Mercy Hospital, Department of Surgery, Center for Prospective Trials, Kansas City, United States
Further Information

Publication History

received March 30, 2009

accepted after revision June 06, 2009

Publication Date:
10 September 2009 (online)

Abstract

The use of extracorporeal membrane oxygenation (ECMO) has increased since its inception. As this modality gained wider acceptance, its application in a variety of disease states has increased. The initial use of ECMO required cannulation of both the carotid artery and internal jugular vein (VA ECMO). Ligation of the carotid artery and concern regarding potential long-term sequelae prompted the development of the single cannula venous only (VV ECMO) technique. Various reports in the literature have compared VV ECMO and VA ECMO. We present a review of the literature with regard to both physiology and clinical application.

References

  • 1 Anderson  III  HL, Otsu T, Chapman RA. et al . Venovenous extracorporeal life support in neonates using a double lumen catheter.  ASAIO Trans. 1989;  35 650-653
  • 2 Anderson HL, Snedecor SM, Otsu T. et al . Multicenter comparison of conventional venoarterial access versus venovenous double-lumen catheter access in newborn infants undergoing extracorporeal membrane oxygenation.  J Pediatr Surg. 1993;  28 530-535
  • 3 Bartlett RH, Roloff DW, Cornell RG. et al . Extracorporeal circulation in neonatal respiratory failure: A prospective randomized study.  Pediatrics. 1985;  76 479-487
  • 4 Beca J, Butt W. Extracorporeal membrane oxygenation for refractory septic shock in children.  Pediatrics. 1994;  93 726-729
  • 5 Berdon WE, Baker DH, Amoury R. The role of pulmonary hypoplasia in the progress of newborn infants with diaphragmatic hernia and eventration.  Am J Roentgenol Radium Ther Nucl Med. 1968;  103 413-421
  • 6 Braunwald E, Kloner RA. The stunned myocardium: prolonged, postischemic ventricular heart dysfunction.  Circulation. 1982;  66 1146-1149
  • 7 Cilley RE, Zwischenberger JB, Andrews AF. et al . Intracranial hemorrhage during extracorporeal membrane oxygenation in neonates.  Pediatrics. 1986;  78 699-704
  • 8 Cornish JD, Heiss KF, Clark RH. et al . Efficacy of venovenous extracorporeal membrane oxygenation for neonates with respiratory and circulatory compromise.  J Pediatr. 1993;  122 105-109
  • 9 Delius R, Anderson III H, Schumacher R. et al . Venovenous compares favorably with venoarterial access for extracorporeal membrane oxygenation in neonatal respiratory failure.  J Thorac Cardiovasc Surg. 1993;  106 329-338
  • 10 Dimmit RA, Moss RL, Rhine WD. et al . Venoarterial versus venovenous extracorporeal membrane oxygenation in congenital diaphragmatic hernia: the Extracorporeal Life Support Organization Registry, 1990–1999.  J Pediatr Surg. 2001;  36 1199-1204
  • 11 ELSO Registry . Extracorporeal Life Support Organization. July 2007; 
  • 12 Finer NN, Tierney AJ, Ainsworth W. Venovenous extracorporeal membrane oxygenation: The effects of proximal internal jugular cannulation.  J Pediatr Surg. 1996;  31 1391-1395
  • 13 Fukuda S, Aoyama M, Yamada Y. et al . Comparison of venoarterial versus venovenous access in the cerebral circulation of newborns undergoing extracorporeal membrane oxygenation.  Pediatr Surg Int. 1999;  15 78-84
  • 14 Hardart GE, Fackler JC. Predictors of intracranial hemorrhage during neonatal extracorporeal membrane oxygenation.  J Pediatr. 1999;  134 156-159
  • 15 Heiss KF, Clark RH, Cornish JD. et al . Preferential use of venovenous extracorporeal membrane oxygenation for congenital diaphragmatic hernia.  J Pediatr Surg. 1995;  30 416-419
  • 16 Hirschl RB, Heiss KF, Bartlett RH. Severe myocardial dysfunction during extracorporeal membrane oxygenation.  J Pediatr Surg. 1992;  27 48-53
  • 17 Hocker JR, Simpson PM, Rabalais GP. et al . Extracorporeal membrane oxygenation and early-onset group B streptococcal sepsis.  Pediatrics. 1992;  89 1-4
  • 18 Horwitz JR, Elarian LF, Sparks JW. et al . Use of extracorporeal membrane oxygenation in the septic neonate.  J Pediatr Surg. 1995;  30 813-815
  • 19 Kinsella JP, Gertsmann DR, Rosenberg AA. The effects of extracorporeal membrane oxygenation on coronary perfusion and regional blood distribution.  Paeditr Res. 1992;  31 80-84
  • 20 Kornhausen MS, Gilbert PL, Desai HG. The efficacy of extracorporeal membrane oxygenation (ECMO) in meconium aspiration and group B streptococcal pneumonia.  Pediatr Res. 1988;  23 414A , (abstr)
  • 21 Kugelman A, Gangitano E, Pincros J. et al . Venovenous versus venoarterial extracorporeal membrane oxygenation in congenital diaphragmatic hernia.  J Pediatr Surg. 2003;  38 1131-1136
  • 22 Kugelman A, Gangitano E, Taschuk R. et al . Extracorporeal membrane oxygenation in infants with meconium aspiration syndrome: a decade of experience with venovenous ECMO.  J Pediatr Surg. 2005;  40 1082-1089
  • 23 Langham  Jr  MR, Kays DW, Ledbetter DJ. et al . Congenital diaphragmatic hernia: epidemiology and outcome.  Clin Perinatol. 1996;  23 671-688
  • 24 Luyt DK, Pridgeon J, Brown J. et al . Extracorporeal life support for children with meningococcal septicemia.  Acta Paediatr. 2004;  93 1608-1611
  • 25 MacLaren G, Butt W, Best D. et al . Extracorporeal membrane oxygenation for refractory septic shock in children: one institution's experience.  Pediatr Crit Care Med. 2007;  8 447-451
  • 26 McCune S, Short BL, Miller MK. et al . Extracorporeal membrane oxygenation therapy in neonates with septic shock.  J Pediatr Surg. 1990;  25 479-482
  • 27 Meyer DM, Jessen M. Extracorporeal life support organization: results of extracorporeal membrane oxygenation in children with sepsis.  Ann Thorac Surg. 1997;  63 756-761
  • 28 O’Connor TA, Haney BM, Crist GE. et al . Decreased incidence of intracranial hemorrhage using cephalic jugular venous drainage during neonatal extracorporeal membrane oxygenation.  J Pediatr Surg. 1993;  28 1332-1335
  • 29 Pape KE. Etiology and pathogenesis of intraventricular hemorrhage in newborns.  Pediatrics. 1989;  84 382-385
  • 30 Roberts N, Westrope C, Pooboni SK. et al . Venovenous extracorporeal membrane oxygenation for respiratory failure in inotrope dependent neonates.  ASAIO Journal. 2003;  49 568-571
  • 31 Skarsgard ED, Salt DR, Lee SK. and the Extracorporeal Life Support Organization Registry . Venovenous extracorporeal membrane oxygenation in neonatal respiratory failure: does routine cephalad jugular drainage improve outcome.  J Pediatr Surg. 2004;  39 672-676
  • 32 Strieper MJ, Sharma S, Dooley KJ. et al . Effects of venovenous extracorporeal membrane oxygenation on cardiac performance as determined by echocardiographic measurements.  J Pediatr. 1993;  122 950-955
  • 33 Wiswell TE. Advances in the treatment of the meconium aspiration syndrome.  Acta Paediatr Suppl. 2001;  436 28-30

Correspondence

Dr. Shawn David St. Peter

Children's Mercy Hospital

Department of Surgery

Center for Prospective Trials

2401 Gillham Road

Kansas City

United States

MO 64108

Phone: +1-816-983 3575

Fax: +1-816-983 6885

Email: sspeter@cmh.edu

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