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Synfacts 2010(6): 0721-0721  
DOI: 10.1055/s-0029-1219899
Polymer-Supported Synthesis
© Georg Thieme Verlag Stuttgart ˙ New York

Suzuki Coupling with Molecular Sieves Supported Palladium Catalyst

Contributor(s): Yasuhiro Uozumi, Noboru Kobayashi
R. Dey, B. Sreedhar, B. C. Ranu*
Indian Association for the Cultivation of Science, Kolkata and Indian Institute of Chemical Technology, Hyderabad, India
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Publication History

Publication Date:
20 May 2010 (online)

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Significance

Molecular sieves supported PdCl2 (ms-PdCl2) catalyzed the Suzuki coupling of aryl chlorides with aryl boronic acids to afford the corresponding biaryl products in up to 98% yield (17 examples). In the reaction of 4-chlorobenzaldehyde with phenylboronic acid, the catalyst was recovered and reused five times without significant loss of activity.