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Synfacts 2010(2): 0215-0215  
DOI: 10.1055/s-0029-1219061
Metal-Mediated Synthesis
© Georg Thieme Verlag Stuttgart ˙ New York

An Aromatic Glaser-Hay Reaction

Contributor(s): Paul Knochel, Andrei Gavryushin
H.-Q. Do, O. Daugulis*
University of Houston, USA
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Publication History

Publication Date:
21 January 2010 (online)

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Significance

Deprotonative dimerization of arenes using oxygen as terminal oxidant represents a new, interesting, and synthetically useful way for the preparation of symmetric functionalized biaryls and less available heterobiaryls like bipyrazines and bitriazoles. The reaction protocol is very simple and practical.