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Horm Metab Res 1971; 3(6): 437-442
DOI: 10.1055/s-0028-1094119
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© Georg Thieme Verlag KG Stuttgart · New York

Effects of Altered Thyroid Function Upon Cortisol Secretion in Man

G.  Copinschi , R.  Leclercq , O. D. Bruno , A.  Cornil
  • Clinique Médicale, Laboratoires de Médecine Expérimentale, de Chimie Clinique et-de Physiopathologie, Université Libre de Bruxelles, Bruxelles, Belgium
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Publication History

Publication Date:
08 January 2009 (online)

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Abstract

The adrenocortical function was studied in adult patients with hyperthyroidism or with myxoedema. In 19 hyperthyroid women, the Cortisol secretion rate was significantly increased (30.6 ± 7.4 mg/d vs 17.8 ± 4.8 mg/d in normal controls); it was significantly decreased in 14 hypothyroid patients (13.7 ± 5.0 mg/d vs 20.5 ± 5.4 mg/d in matched controls). Changes in urinary excretion of Cortisol metabolites were more pronounced than in Cortisol secretion. Adrenocortical modifications were mostly reversible after recovery.

Key words

Cortisol Secretion in Hyperthyroidism - Cortisol Secretion in Hypothyroidism - Excretion of 17-Ketogenic Steroids in Hyperthyroidism - Excretion of 17-Ketogenic Steroids in Hypothyroidism

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