Semin Neurol
DOI: 10.1055/a-2730-8997
Review Article

Artificial Intelligence and Multiple Sclerosis: Past, Present, and Future

Autor*innen

  • Moein Amin

    1   Mellen Center for Multiple Sclerosis Treatment and Research, Cleveland Clinic, Cleveland, Ohio, United States
  • Kunio Nakamura

    2   Department of Biomedical Engineering, Cleveland Clinic Research, Cleveland Clinic, Cleveland, Ohio, United States
  • Daniel Ontaneda

    1   Mellen Center for Multiple Sclerosis Treatment and Research, Cleveland Clinic, Cleveland, Ohio, United States

Abstract

Artificial intelligence (AI) in multiple sclerosis (MS) is an area of growing importance of growing importance. We review the historical context, current applications, and future prospects of AI and machine learning (ML) in MS. The review highlights AI's potential to address critical challenges in MS management, including early and accurate diagnosis, individualized treatment strategies, prognostication, and efficient patient monitoring. By leveraging large datasets and high-dimensional data, AI promises profound insights and augments clinical decision-making processes. Additionally, the manuscript covers potential limitations and challenges facing AI use in MS clinical practice and research.

Declaration of GenAI Use

Portions of [Fig. 1] were generated using generative artificial intelligence tool, Google Gemini.




Publikationsverlauf

Eingereicht: 25. Juli 2025

Angenommen: 21. Oktober 2025

Artikel online veröffentlicht:
10. November 2025

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