Die Körperkomposition vor allogener hämatopoetischer Stammzelltransplantation und ihre Beinflussbarkeit durch Vibrationstraining während der Therapie

Zusammenfassung

Die allogene hämatopoetische Stammzelltransplantation (alloHSZT) ist eine intensive Therapie zur Behandlung hämatologischer (Krebs-)Erkrankungen und ist mit einem erheblichen negativen Einfluss auf die Körperkomposition verbunden. Patienten verlieren stark an Gewicht, v. a. Muskelmasse, wodurch es zu Einschränkungen der körperlichen Leistungsfähigkeit, bis hin zu kritischen Gesundheitszuständen kommt. Demnach haben Patienten, die mit einer größeren Körper- und Muskelmasse und einem höheren Phasenwinkel α (in der Bio-Impedanz-Analyse) in die Therapie starten, ein geringeres Mortalitäts- und Morbiditätsrisiko. Durch ein individuelles, personalisiertes Bewegungsprogramm während der alloHSZT kann zusätzlich ein Erhalt der körperlichen Leistungsfähigkeit erreicht werden. Hierbei stellte sich Vibrationstraining als eine geeignete Trainingsform heraus.

Abstract

The allogeneic hematopoietic stem cell transplantation (alloHSCT) is a very intensive therapy for the treatment of hematological (cancer) diseases and is associated with a significant negative impact on body composition. Patients lose a lot of weight and muscle mass causing limitations in physical performance, up to critical health conditions. Accordingly, patients with higher body and muscle mass and greater phase angle α have a better chance of overall survival. Additionally, an individual exercise program during alloHSCT can also help to maintain physical performance. Vibration training proved to be suitable for patients during alloHSCT.

Schlüsselwörter

Muskelmasse - Risikofaktor - Hämatoonkologie - körperliche Aktivität - Phasenwinkel

Keywords

muscle mass - risk factor - heamato-oncology - physical exercise - phase angle

Publication History

Received: 04 March 2025

Accepted: 07 April 2025

Article published online:
05 December 2025

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