CAR-T-Zellen und bispezifische Antikörper: neue Optionen für Non-Hodgkin-Lymphome

Binnen weniger Jahre hat sich das therapeutische Arsenal gegen Non-Hodgkin-Lymphome drastisch verändert. Mit mehreren Zulassungen sind CAR-T-Zellen und bispezifische Antikörper mittlerweile fester Bestandteil der Therapie rezidivierter oder refraktärer Fälle. In Zukunft werden sich die Indikationen aller Wahrscheinlichkeit nach weiter ausdehnen und unter Umständen teilweise sogar die Erstlinie erreichen.

Schlüsselwörter

diffuses großzelliges B-Zell-Lymphom - follikuläres Lymphom - Non-Hodgkin-Lymphom - CAR-T-Zellen - bispezifische Antikörper

• Literatur

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