Reagent-Free Esterification from Benzoyl Hydrazines and Alcohols under Electrochemical Conditions

Abstract

A scalable electrochemical esterification between aroylhydrazides and alcohols to give structurally versatile carboxylic esters was developed. This strategy features mild reaction conditions and a relatively broad substrate scope with good functional group compatibility. In addition, the transformation is operationally simple and free from external oxidants and mediating chemical reagents.

Key words

electrochemical synthesis - esterification - aroylhydrazides - reagent-free reaction - anode oxidation

Publication History

Received: 19 December 2022

Accepted after revision: 28 February 2023

Accepted Manuscript online:
28 February 2023

Article published online:
09 May 2023

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