Erfolgreiche lokale Behandlung eines digitalen kaninen Mastzelltumors mit Tigilanoltiglat

Zusammenfassung

Die chirurgische Entfernung ist derzeit die Standardtherapie für resezierbare, nicht-metastasierte Mastzelltumoren (MZT). Seit kurzem steht mit dem intratumoral angewendeten Tigilanoltiglat eine neue Therapieoption für ausgewählte kutane und subkutane MZT zur Verfügung. Hier wird die erfolgreiche Behandlung eines 0,445 cm³ großen subkutanen MZTs an der Zehe eines American Staffordshire Terriers dokumentiert. Die daraus resultierende Wunde heilte komplikationslos innerhalb von 4 Wochen vollständig ab, und der Hund zeigte 8 Monate nach Therapie kein Rezidiv. Dank des neuen Medikaments konnte die Zehe erhalten werden, während chirurgisch eine vollständige Entfernung des Tumors nur mittels Amputation der Zehe möglich gewesen wäre.

Abstract

Surgical excision is currently the recommended treatment for resectable, nonmetastatic mast cell tumours. Recently, Tigilanol tiglate has become available as a novel intratumoral treatment modality for a subset of cutaneous and subcutaneous mast cell tumours. In the presented case, we document the successful treatment of a 0.445 cm³ subcutaneous digital mast cell tumour in an American Staffordshire Terrier. The resulting wound healed completely and without complications within 4 weeks and the dog was recurrence-free 8 months after treatment. Due to this new intratumoral treatment it was possible to preserve the digit, while a complete surgical resection of the tumour would have required digital amputation.

Schlüsselwörter

Therapie - Stelfonta - subkutaner Mastzelltumor - intratumoral - Hund - Staffordshire Terrier - Tumor

Key words

Therapy - Stelfonta - subcutaneous mast cell tumour - intratumoral - dog - Staffordshire Terrier

Publication History

Received: 10 May 2021

Accepted: 30 September 2021

Article published online:
05 July 2022

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