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Int J Sports Med 2019; 40(03): 171-179
DOI: 10.1055/a-0810-8533
Physiology & Biochemistry
© Georg Thieme Verlag KG Stuttgart · New York

Late Neutrophil Priming Following a Single Session of High-intensity Interval Exercise

Vinícius de Oliveira Ottone
1   Centro Integrado de Pós-graduação e Pesquisa em Saúde (CIPq-saúde), Multicentric Graduate Program in Physiological Sciences, Universidade Federal dos Vales do Jequitinhonha e Mucuri (UFVJM), Diamantina, Brazil
,
Karine Beatriz Costa
1   Centro Integrado de Pós-graduação e Pesquisa em Saúde (CIPq-saúde), Multicentric Graduate Program in Physiological Sciences, Universidade Federal dos Vales do Jequitinhonha e Mucuri (UFVJM), Diamantina, Brazil
,
Rosalina Tossige-Gomes
1   Centro Integrado de Pós-graduação e Pesquisa em Saúde (CIPq-saúde), Multicentric Graduate Program in Physiological Sciences, Universidade Federal dos Vales do Jequitinhonha e Mucuri (UFVJM), Diamantina, Brazil
,
Mariana Aguiar de Matos
1   Centro Integrado de Pós-graduação e Pesquisa em Saúde (CIPq-saúde), Multicentric Graduate Program in Physiological Sciences, Universidade Federal dos Vales do Jequitinhonha e Mucuri (UFVJM), Diamantina, Brazil
,
Gustavo Brito-Melo
1   Centro Integrado de Pós-graduação e Pesquisa em Saúde (CIPq-saúde), Multicentric Graduate Program in Physiological Sciences, Universidade Federal dos Vales do Jequitinhonha e Mucuri (UFVJM), Diamantina, Brazil
2   Dept of Pharmacy, UFVJM, Brazil
,
Flavio de Castro Magalhaes
1   Centro Integrado de Pós-graduação e Pesquisa em Saúde (CIPq-saúde), Multicentric Graduate Program in Physiological Sciences, Universidade Federal dos Vales do Jequitinhonha e Mucuri (UFVJM), Diamantina, Brazil
3   Dept of Physical Education, UFVJM, Brazil
,
Elizabethe Adriana Esteves
1   Centro Integrado de Pós-graduação e Pesquisa em Saúde (CIPq-saúde), Multicentric Graduate Program in Physiological Sciences, Universidade Federal dos Vales do Jequitinhonha e Mucuri (UFVJM), Diamantina, Brazil
4   Dept of Nutrition, UFVJM
,
Fabiano Amorim
1   Centro Integrado de Pós-graduação e Pesquisa em Saúde (CIPq-saúde), Multicentric Graduate Program in Physiological Sciences, Universidade Federal dos Vales do Jequitinhonha e Mucuri (UFVJM), Diamantina, Brazil
5   Dept of Heatlh, Exercise & Sports Sciences, University of New Mexico, Albuquerque, USA
,
Etel Rocha-Vieira
1   Centro Integrado de Pós-graduação e Pesquisa em Saúde (CIPq-saúde), Multicentric Graduate Program in Physiological Sciences, Universidade Federal dos Vales do Jequitinhonha e Mucuri (UFVJM), Diamantina, Brazil
6   Faculty of Medicine, UFVJM, Brazil
› Author Affiliations
Further Information

Publication History



accepted 28 November 2018

Publication Date:
31 January 2019 (online)

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Abstract

This study evaluated the effect of an acute high-intensity interval exercise (HIIE) session on the function of human neutrophils. Twelve sedentary men performed a HIIE session (8 bouts of 60 s at 90% of peak power, intercalated with 75 s of active recovery at 30 W). Neutrophils were collected before, 30 min and 24 h after the exercise session for the evaluation of phagocytic capacity, expression of phagocytic receptors, reactive oxygen species generation, and redox status. 24 h after the HIIE session, an increase was observed in both neutrophil phagocytic capacity and yeast-induced generation of reactive oxygen species, which indicates neutrophil priming in response to an acute HIIE session. Neutrophils also presented an increase in superoxide dismutase activity 24 h after the exercise. Improvement in neutrophil function was accompanied by increased serum levels of IL-8 and increased concentration of plasma lactate dehydrogenase. Our findings show a late activating effect of one HIIE session on neutrophils. We propose that priming of neutrophils by HIIE may play a role in skeletal muscle inflammation after exercise.

Key words

phagocytosis - superoxide dismutase - reactive oxygen species - inflammation
 

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