Oropharynx-Karzinom-CT: prognostische Bedeutung der extranodalen Ausbreitung

Patel MR et al. Radiographic Imaging Does Not Reliably Predict Macroscopic Extranodal Extension in Human Papilloma Virus-Associated Oropharyngeal Cancer. ORL 2018; 80: 85–95

Amerikanische Radiologen und Fachärzte für Otorhinolaryngologie evaluierten bei Patienten mit Oropharynx-Plattenepithelkarzinomen (OPSCC) die Genauigkeit der präoperativen kontrastmittelverstärkten Computertomographie (CECT), um die extranodale Ausdehnung (ENE) (> 2 mm) zu prognostizieren.

• Literatur

• 1 Mermod M. et al. Extracapsular spread in head and neck squamous cell carcinoma: A systematic review and meta-analysis. Oral Oncol 2016; 62: 60-71 doi:10.1016/j.oraloncology.2016.10.003
• 2 An Y. et al. The prognostic value of extranodal extension in human papillomavirus-associated oropharyngeal squamous cell carcinoma. Cancer 2017; 123: 2762-2772 doi:10.1002/cncr.30598
• 3 Geltzeiler M. et al. Predictors of extracapsular extension in HPV-associated oropharyngeal cancer treated surgically. Oral Oncol 2017; 65: 89-93 doi:10.1016/j.oraloncology.2016.12.025
• 4 Yousem DM. et al. Central nodal necrosis and extracapsular neoplastic spread in cervical lymph nodes: MR imaging versus CT. Radiology 1992; 182: 753-9
• 5 King AD. et al. Comparison of CT and MR imaging for the detection of extranodal neoplastic spread in metastatic neck nodes. Eur J Radiol 2004; 52: 264-70
• 6 Steinkamp HJ. et al. Extracapsular spread of cervical lymph node metastases: diagnostic relevance of ultrasound examinations. Ultraschall Med 2003; 24: 323-30
• 7 Subramaniam RM. et al. PET/CT imaging and human papilloma virus-positive oropharyngeal squamous cell cancer: evolving clinical imaging paradigm. J Nucl Med 2014; 55: 431-8 doi:10.2967/jnumed.113.125542
• 8 Coatesworth AP. et al. Squamous cell carcinoma of the upper aerodigestive tract: the prevalence of microscopic extracapsular spread and soft tissue deposits in the clinically N0 neck. Head Neck 2002; 24: 258-61