DOI: 10.1055/s-00000084

Synthesis

References

Process Mass Intensity (PMI) is the total mass of raw materials input divided by the mass of final Active Pharmaceutical Ingredient (API) output. It is one of the benchmarks to measure the environmental impact and sustainability of chemical processes. For a review of such benchmarks, see: Constable DJ. C, Curzons AD, Cunningham VL.
Green Chem. 2002;
4: 521

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