DOI: 10.1055/s-00023610

Drug Research

eFirst

Publication Date: 12 September 2018

Original Article

Bhat, Aashiq Hussain; Dar, Khalid Bashir; Zargar, Mohammad Afzal; Masood, Akbar; Ganie, Showkat Ahmad: Modulation of Oxidative Stress and Hyperglycemia by Rheum spiciformis in Alloxan Induced Diabetic Rats and Characterization of Isolated Compound

Publication Date: 07 September 2018

Original Article

Devi, Poornima; Bishnoi, Abha; Srivastava, Krishna; Kumar, Sunil; Srivastava, Ankita; Fatma, Shaheen: Synthesis and Biological Evaluation of Novel 5-Oxo-1-Phenylpyrrolidine-3-Carboxylic Acid Analogs
Supporting Information

Original Article

Dixit, Abhishek; Mallurwar, Sadanand Rangnathrao; Sulochana, Suresh P; Zainuddin, Mohd; Mullangi, Ramesh: Determination of Tofacitinib in Mice Whole Blood on Dried Blood Spots Using LC–ESI–MS/MS: Application to Pharmacokinetic Study in Mice

Original Article

Hara, Johsuke; Kasahara, Kazuo; Ohkura, Noriyuki; Yamamura, Kenta; Sakai, Tamami; Abo, Miki; Ogawa, Naohiko; Saeki, Keigo; Koba, Hayato; Watanabe, Satoshi; Uchida, Yuka; Tambo, Yuichi; Sone, Takashi; Kimura, Hideharu: A Single Institution Retrospective Study of the Clinical Efficacy of Tiotropium Respimat in Never-Smoking Elderly Asthmatics with Irreversible Airflow Limitation

Original Article

Li, Xingang; Sun, Shusen; Xu, Xiaowei; Zhao, Zhigang; Li, Wei: The Association between Genetic Polymorphisms and Simvastatin-Induced Myopathy: A Narrative Synthesis of Evidence

Original Article

Li, Xiumin; Xue, Yu; Pang, Liang; ShangGuan, Zhaoshui; Pan, Yutian: Lysimachia Capillipes Inhibit Adipogenesis via Angiogenesis Inhibition

Original Article

Sridharan, Kannan; Sivaramakrishnan, Gowri: Which Antimicrobial Agent is Likely to be the Best for Treating Clostridium difficile Infections? A Bayesian Network Meta-Analysis of Randomized Clinical Trials

Publication Date: 06 September 2018

Original Article

Danysz, Wojciech; Jinlai, Kang; Li, Fugang: Duration of a ”Brown-Like” Phenotype of White Adipose Tissue Induced by the β3 Agonist CL-316,243

Original Article

Estuningtyas, Ari; Setiabudy, Rianto; Wahidiyat, Pustika Amalia; Freisleben, Hans-Joachim: The Role of Mangiferin in the Prevention of Experimentally Induced Iron Overload in an Animal Model

Original Article

Nosrati, Hamed; Hamzehei, Hossein; Afroogh, Saeed; Ashabi, Seyedeh Fatemeh; Attari, Elahe; Manjili, Hamidreza Kheiri: Phenyl alanine & Tyrosine Amino acids Coated Magnetic Nanoparticles: Preparation and Toxicity study

Publication Date: 24 August 2018

Erratum

Oskouei, Bijan Ghorbanpour; Abbaspour-Ravasjani, Soheil; Jamal Musavinejad, Seyed; Ahmad Salehzadeh, Seyed; Abdolhosseinzadeh, Alireza; Hamishehkar, Hamed; Ghahremanzadeh, Kazem; Shokouhi, Behrooz: Correction: In vivo Evaluation of Anti-Hyperglycemic, Anti-hyperlipidemic and Anti-Oxidant Status of Liver and Kidney of Thymol in STZ-Induced Diabetic Rats

Publication Date: 22 August 2018

Original Article

Vilhelmova-Ilieva, Neli; Jacquet, Rémi; Deffieux, Denis; Pouységu, Laurent; Sylla, Tahiri; Chassaing, Stefan; Nikolova, Ivanka; Quideau, Stéphane; Galabov, Angel S.: Anti-Herpes Simplex Virus Type 1 Activity of Specially Selected Groups of Tannins

Publication Date: 13 August 2018

Original Article

Houshaymi, Bilal; Nasreddine, Nadine; Kedees, Mamdouh; Soayfane, Zeina: Oleic acid increases uptake and decreases the P-gp-mediated efflux of the veterinary anthelmintic Ivermectin

Original Article

Ikeda, Sachiya; Takano, Yasuki; Schwab, Dietmar; Portron, Agnes; Kasahara-Ito, Nahoko; Saito, Tomohisa; Iida, Satofumi: Effect of Renal Impairment on the Pharmacokinetics and Pharmacodynamics of Tofogliflozin (A SELECTIVE SGLT2 Inhibitor) in Patients with Type 2 Diabetes Mellitus
Supporting Information

Original Article

Nagai, Katsuhito; Omotani, Sachiko; Ito, Akihiko; Nishimura, Ikumi; Hatsuda, Yasutoshi; Mukai, Junji; Teramachi, Hitomi; Myotoku, Michiaki: Alterations in Pharmacokinetics of Orally Administered Carbamazepine in Rats Treated with Sodium alginate: Possible Interaction between Therapeutic Drugs and Semi-solid Enteral Nutrients

Original Article

Oskouei, Bijan Ghorbanpour; Abbaspour-Ravasjani, Soheil; Jamal Musavinejad, Seyed; Ahmad Salehzadeh, Seyed; Abdolhosseinzadeh, Alireza; Hamishehkar, Hamed; Ghahremanzadeh, Kazem; Shokouhi, Behrooz: In vivo Evaluation of Anti-Hyperglycemic, Anti-hyperlipidemic and Anti-Oxidant Status of Liver and Kidney of Thymol in STZ-Induced Diabetic Rats

Publication Date: 07 August 2018

Original Article

Abbasi, Muhammad Athar; Raza, Hussain; Rehman, Aziz ur; Siddiqui, Sahahat Zahra; Nazir, Majid; Mumtaz, Ayesha; Shah, Syed Adnan Ali; Seo, Sung-Yum; Hassan, Mubashir: Synthesis, Antioxidant and In-Silico Studies of Potent Urease Inhibitors: N-(4-{[(4-Methoxyphenethyl)-(substituted)amino]sulfonyl}phenyl)acetamides
Supporting Information

Original Article

Karami, Zahra; Khoshkam, Maryam; Hamidi, Mehrdad: Optimization of Olive Oil-Based Nanoemulsion Preparation for Intravenous Drug Delivery

Publication Date: 06 August 2018

Original Article

Moezi, Leila; Yahosseini, Siranoush; Jamshizadeh, Akram; Pirsalami, Fateme: Acute Boldine Treatment Induces Anti-convulsant Effects in Mice through its Antioxidant Activity

Publication Date: 03 August 2018

Original Article

Salako, Olanrewaju A.; Akindele, Abidemi J.; Balogun, Aishat O.; Adeyemi, Olufunmilayo O.: Investigation of Antidepressant, Anxiolytic and Sedative Activities of the Aqueous Leaf Extract of Musa sapientum Linn. (Banana; Musaceae)

Publication Date: 02 August 2018

Original Article

Adeoluwa, Adebayo O.; Aderibigbe, Oladele A.; Agboola, Isaiah O.; Olonode, Toyin E.; Ben-Azu, Benneth: Butanol Fraction of Olax Subscorpioidea Produces Antidepressant Effect: Evidence for the Involvement of Monoaminergic Neurotransmission

Publication Date: 31 July 2018

Original Article

Ajayi, Abayomi M.; Ben-Azu, Benneth; Onasanwo, Samuel A.; Adeoluwa, Olusegun; Eduviere, Anthony; Ademowo, Olusegun G: Flavonoid-Rich Fraction of Ocimum gratissimum Attenuates Lipopolysaccharide-Induced Sickness Behavior, Inflammatory and Oxidative Stress in Mice

Publication Date: 30 July 2018

Original Article

Noei, Ahmad; Nili-Ahmadabadi, Amir; Soleimani, Meysam: The Enhanced Cytotoxic Effects of the p28-Apoptin Chimeric Protein As A Novel Anti-Cancer Agent on Breast Cancer Cell Lines

Review

Mahmood, Danish: Pleiotropic Effects of Melatonin

Publication Date: 24 July 2018

Original Article

Theivendren, Panneerselvam; Kunjiappan, Selvaraj; Govindraj, Saravanan; Chandrasekarn, Jaikanth; Pavadai, Parasuraman; Saraswathy, Ganesan Rajalekshmi; Murugan, Indhumathy: Graph Theoretical Analysis, Insilico Modeling and Formulation of Pyrimidine Nanoparticles as p38α MAP Kinases inhibitors: A Quantitative Proteomics Approach
Supporting Information

Publication Date: 23 July 2018

Original Article

Kumar, Parvin; Kumar, Ashwani; Sindhu, Jayant; Lal, Sohan: QSAR Models for Nitrogen Containing Monophosphonate and Bisphosphonate Derivatives as Human Farnesyl Pyrophosphate Synthase Inhibitors Based on Monte Carlo Method
Supporting Information

Publication Date: 18 July 2018

Erratum

Omóbòwálé, Temidayo Olutayo; Oyagbemi, Ademola Adetokunbo; Ogunpolu, Blessing Seun; Ola-Davies, Olufunke Eunice; Olukunle, Johnny Olufemi; Asenuga, Ebunoluwa Racheal; Ajibade, Temitayo Olabisi; Adejumobi, Olumuyiwa Abiola; Afolabi, Jeremiah Moyinoluwa; Falayi, Olufunke Olubunmi; Ashafa, Anofi; Adedapo, Adeolu Alex; Yakubu, Momoh Audu: Correction: Antihypertensive Effect of Polyphenol-Rich Fraction of Azadirachta indica on Nω-Nitro-L-Arginine Methyl Ester-Induced Hypertension and Cardiorenal Dysfunction

Publication Date: 11 July 2018

Original Article

Adedara, Isaac A.; Alake, Sanmi E.; Olajide, Laide O.; Adeyemo, Mercy O.; Ajibade, Temitayo O.; Farombi, Ebenezer O.: Taurine Ameliorates Thyroid Hypofunction and Renal Injury in L-NAME-Induced Hypertensive Rats

Original Article

Jairam, Ravi Kumar; Mallurwar, Sadanand Rangnathrao; Sulochana, Suresh P; Chandrasekar, Devaraj V; Bhamidipati, Ravi Kanth; Richter, Wolfgang; Srinivas, Nuggehally R.; Mullangi, Ramesh: Prediction of Human Pharmacokinetics of Bendamustine from Preclinical Species Pharmacokinetics Based on Normalizing Time Course Profiles

Original Article

Mohammadi-Aghdam, Sarvin; Valinezhad-Saghezi, Bahareh; Mortazavi, Yousef; Qhoreishi, Seyedeh Masoumeh: Modified Fe3O4/HAp Magnetically Nanoparticles as the Carrier for Ibuprofen: Adsorption and Release Study

Original Article

Mohammadpour, Abbas; Ashkezari, Mahmood Dehghani; Farahmand, Behrokh; Shokrzadeh, Mohammad: Demographic Characteristics and Functional Performance of the Kidneys and Hearts of Patients with Acute Tramadol Toxicity

Publication Date: 10 July 2018

Original Article

Perdigão, Ana P. L.; Antunes, Natalícia de Jesus; Juni, Lucas T.; de Freitas, Noedi L.; Rojas-Moscoso, Julio; Corrêa, Sílvia V. M.; da Costa, Ronaldo C.; Moreno, Ronilson A.; Mendes, Gustavo D.; De Nucci, Gilberto: Pharmacokinetics of Riluzole in Beagle Dogs

Publication Date: 02 July 2018

Original Article

Kusunoki, Masataka; Natsume, Yukie; Miyata, Tetsuro; Tsutsumi, Kazuhiko; Oshida, Yoshiharu: Effects of Concomitant Administration of Sodium Glucose Co-transporter 2 Inhibitor with Insulin on Hemoglobin A1c, Body Mass Index and Serum Lipid Profile in Japanese Type 2 Diabetic Patients

Original Article

Kusunoki, Masataka; Natsume, Yukie; Miyata, Tetsuro; Tsutsumi, Kazuhiko; Oshida, Yoshiharu: Effects of Concomitant Administration of a Dipeptidyl Peptidase-4 Inhibitor in Japanese Patients with Type 2 Diabetes Showing Relatively Good Glycemic Control Under Treatment with a Sodium Glucose Co-Transporter 2 Inhibitor

Original Article

Li, Wanqing; Ba, Hongyuan; Huang, Peng; Zheng, Aiping; Yang, Xi: Preparation and Properties of 5-Fluorouracil-Loaded Chitosan Microspheres for the Intranasal Administration

Publication Date: 26 June 2018

Original Article

Akinjiola, Akinwale Modupe; Ajala, Oluwatoyin Oluwasola; Aina, Oluwasanmi Olayinka; Oyebanji, Victor Olawale; Olukunle, Johnny Olufemi: Histomorphometry and Protein Expression From the Ovary and Uterine Horns of Wistar Strain Albino Rats Treated with Methanol Leave Extract of Parquetina Nigrescens

Original Article

Busari, Abdulwasiu A.; Adejare, Abdullahi A.; Shodipe, Abiodun F.; Oduniyi, Oludaisi A.; Ismail-Badmus, Khadijah B.; Oreagba, Ibrahim A.: Protective but Non-Synergistic Effects of Nigella Sativa and Vitamin E against Cisplatin-Induced Renal Toxicity and Oxidative Stress in Wistar Rats

Original Article

Soetikno, Vivian; Sari, Shinta Dewi Permata; Ul Maknun, Lulu; Sumbung, Nielda Kezia; Rahmi, Deliana Nur Ihsani; Pandhita, Bashar Adi Wahyu; Louisa, Melva; Estuningtyas, Ari: Pre-Treatment with Curcumin Ameliorates Cisplatin-Induced Kidney Damage by Suppressing Kidney Inflammation and Apoptosis in Rats

Review

Isiordia-Espinoza, Mario Alberto; Bologna-Molina, Ronell Eduardo; Hernández-Miramontes, Ycenna Ailed; Zapata-Morales, Juan Ramón; Alonso-Castro, Angel Jobsabad; Martínez-Morales, Flavio; Sánchez-Enriquez, Sergio; Serafín-Higuera, Nicolás Addiel; Pérez-Cortez, Guillermo; Franco-de la Torre, Lorenzo: Pharmacological Control of Complications Following to Third Molar Removal: Evidence Based on A Meta-Analysis

Publication Date: 19 June 2018

Original Article

Chatran, Mina; Pilehvar-Soltanahmadi, Younes; Dadashpour, Mehdi; Faramarzi, Leila; Rasouli, Sara; Jafari-Gharabaghlou, Davoud; Asbaghi, Navid; Zarghami, Nosratollah: Synergistic Anti-proliferative Effects of Metformin and Silibinin Combination on T47D Breast Cancer Cells via hTERT and Cyclin D1 Inhibition

Original Article

Omóbòwálé, Temidayo Olutayo; Oyagbemi, Ademola Adetokunbo; Ogunpolu, Blessing Seun; Ola-Davies, Olufunke Eunice; Olukunle, Johnny Olufemi; Asenuga, Ebunoluwa Racheal; Ajibade, Temitayo Olabisi; Adejumobi, Olumuyiwa Abiola; Afolabi, Jeremiah Moyinoluwa; Falayi, Olufunke Olubunmi; Ashafa, Anofi; Adedapo, Adeolu Alex; Yakubu, Momoh Audu: Antihypertensive Effect of Polyphenol-Rich Fraction of Azadirachta indica on Nω-Nitro-L-Arginine Methyl Ester-Induced Hypertension and Cardiorenal Dysfunction

Publication Date: 12 June 2018

Original Article

Mukherjee, Prasun; Das, Asish R.; Mishra, Raghwendra; Bhowmick, Shovonlal; Saha, Achintya: Synthesis of Novel tricyclic pyrazolo(1,4)oxathiinopyrazines and Evaluation of Their Competency Towards the Inhibition of Lactate Dehydrogenase Activity-Inhibition of LDH Activity
Supporting Information

Original Article

Prasaja, Budi; Syabani, M. Maulana; Sari, Endah; Chilmi, Uci; Cahyaningsih, Prawitasari; Kosasih, Theresia Weliana: In-vitro Equilibrium Phosphate Binding Study of Sevelamer Carbonate by UV-Vis Spectrophotometry
Supporting Information

Publication Date: 25 May 2018

Original Article

Husna, Fauzul; Suyatna, Franciscus D.; Arozal, Wawaimuli; Poerwaningsih, Erni H.: Anti-Diabetic Potential of Murraya Koenigii (L.) and its Antioxidant Capacity in Nicotinamide-Streptozotocin Induced Diabetic Rats

Publication Date: 23 May 2018

Original Article

Zaid, Abdel Naser; Shraim, Naser; Radwan, Asmaa; Jaradat, Nidal; Hirzallah, Samah; Issa, Ibrahim; Khraim, Aya: Does GastroPlus Support Similarity and Dissimilarity Factors of in vitro-in vivo Prediction in Biowaiver Studies? A Lower Strength Amlodipine As a Model Drug

Original Article

Zhao, Kun; Yang, Ming; Lu, Yanxia; Sun, Shusen; Li, Wei; Li, Xingang; Zhao, Zhigang: P2Y12 Polymorphisms and the Risk of Adverse Clinical Events in Patients Treated with Clopidogrel: A Meta-Analysis
Supporting Information

Original Paper

Leifer, Franziska G.; Konicek, Donna M.; Chen, Kuan-Ju; Plaunt, Adam J.; Salvail, Dany; Laurent, Charles E.; Corboz, Michel R.; Li, Zhili; Chapman, Richard W.; Perkins, Walter R.; S. Malinin, Vladimir: Inhaled Treprostinil-Prodrug Lipid Nanoparticle Formulations Provide Long-Acting Pulmonary Vasodilation
Supplementary Information

Publication Date: 14 May 2018

Original Article

Amakali, Klaudia T.; Legoabe, Lesetja J.; Petzer, Anél; Petzer, Jacobus P.: Synthesis and in vitro Evaluation of 2-heteroarylidene-1-tetralone Derivatives as Monoamine Oxidase Inhibitors

Publication Date: 07 May 2018

Original Article

Zargar, Ovais Ahmad; Bashir, Rohina; Ganie, Showkat Ahmad; Masood, Akbar; Zargar, Mohammad Afzal; Hamid, Rabia: Hepatoprotective Potential of Elsholtzia densa Against Acute and Chronic Models of Liver Damage in Wistar Rats
Supporting Information

Publication Date: 02 May 2018

Original Article

Saeedi, Golbahar; Jeivad, Fereshteh; Goharbari, Mohammadhadi; Gheshlaghi, Gholamreza Hassanzadeh; Sabzevari, Omid: Ethanol Extract of Crataegus Oxyacantha L. Ameliorate Dietary Non-Alcoholic Fatty Liver Disease in Rat

Publication Date: 23 April 2018

Original Article

Idkaidek, Nasir; Hamadi, Salim; El-Assi, Manal; Al-Shalalfeh, Ahmad; Al-Ghazawi, Ahmad: Saliva versus Plasma Therapeutic Drug Monitoring of Pregabalin in Jordanian Patients

Publication Date: 18 April 2018

Original Article

Ahmad, Niyaz; Ahmad, Rizwan; Alam, Md Aftab; Ahmad, Farhan Jalees: Quantification and Brain Targeting of Eugenol-Loaded Surface Modified Nanoparticles Through Intranasal Route in the Treatment of Cerebral Ischemia

Publication Date: 17 April 2018

Original Article

Ige, Pradum P.; Pardeshi, Sagar R.; Sonawane, Raju O.: Development of pH-Dependent Nanospheres for Nebulisation- In vitro Diffusion, Aerodynamic and Cytotoxicity Studies

Publication Date: 10 April 2018

Original Article

Haque, Mohammad Rafiul; Ansari, H. Shahid: Anti-Obesity Effect of Arq Zeera and Its Main Components Thymol and Cuminaldehyde in High Fat Diet Induced Obese Rats

Publication Date: 09 April 2018

Original Article

Varshosaz, Jaleh; Ahmadipour, Saeedeh; Tabbakhian, Majid; Ahmadipour, Shokoufeh: Nanocrystalization of Pioglitazone by Precipitation Method

Original Paper

Chen, Xiaojia; Li, Wanqin; Li, Ying; Guo, Fei; Zhang, Hui; Gao, Jing; Sun, Jianxu; Zheng, Aiping: Preparation and Evaluation of Midazolam Rectal Gel in vitro and in vivo

Publication Date: 26 March 2018

Review

Ahmad, Usama; Ahmad, Zeeshan; Khan, Ahmed Abdullah; Akhtar, Juber; Singh, Satya Prakash; Ahmad, Farhan Jalees: Strategies in Development and Delivery of Nanotechnology Based Cosmetic Products

Publication Date: 20 March 2018

Original Article

Balaji, Narayan; Sulochana, Suresh P.; Saini, Neeraj Kumar; A., Siva Kumar; Mullangi, Ramesh: Validated Chiral LC-ESI-MS/MS Method for the Simultaneous Quantification of Darolutamide Diastereomers and Its Active Metabolite in Mice Plasma: Application to a Pharmacokinetic Study

Publication Date: 30 January 2018

Erratum

Bagheri, Raana; Sanaat, Zohreh; Zarghami, Nosratollah: Correction: Synergistic Effect of Free and Nano-encapsulated Chrysin-Curcumin on Inhibition of hTERT Gene Expression in SW480 Colorectal Cancer Cell Line

Publication Date: 05 December 2017

Erratum

Leary, Andrew; Barthe, Laurence; Clavel, Thierry; Sanchez, Claudie; Issiakhem, Zahida; Paillard, Bruno; Edmond, Jean-Marc: Iron Pharmacokinetics in Women with Iron Deficiency Anaemia Following A Single Oral Dose of a Novel Formulation of Tardyferon (Prolonged Release Ferrous Sulphate)