DOI: 10.1055/s-00000131

Synfacts

Issue 06 · Volume 17 · June 2021 DOI: 10.1055/s-011-50925

Synform

  • A88

    SYNFORM ISSUE 2021/06

    • Synthesis of Natural Products and Potential Drugs

  • z0597

    All PDFs of this category

  • 0597

    Total Synthesis of (+)-Alsmaphorazine C

  • 0598

    Synthesis of Alogliptin

  • 0599

    A Refined ProTide Route to Uprifosbuvir

  • 0600

    A Scalable Ring-Closing Metathesis for the Manufacture of AMG 176

  • 0601

    Total Synthesis of (–)-Casuarinine H, (+)-Lycoplatyrine B, and (–)-Dihydrohuperzine A

  • 0602

    Synthesis of (±)-Psychotriadine

  • 0603

    Total Synthesis of (–)-Curcusone Diterpenoids

  • 0604

    Synthesis of Remdesivir via Diastereoselective Organocatalyzed Phosphoramidation

  • 0605

    Synthesis of BAY 1161116

  • 0606

    Synthesis of Abrocitinib

  • 0607

    Synthesis of (+)-Ritterazine B

  • 0608

    Synthesis of MK-7145

  • 0609

    Synthesis of Nemiralisib

  • 0610

    Synthesis of the 2-Fluoroadenine Nucleobase of Islatravir

  • 0611

    Synthesis of (±)-Gymnomitrol

  • 0612

    Collective Synthesis of Cephalotaxus Alkaloids

    • Synthesis of Heterocycles

  • z0613

    All PDFs of this category

  • 0613

    Gold-Catalyzed Synthesis of 2H‑Azirines from Alkynyl N-Sulfinylimines

  • 0614

    Visible-Light-Promoted Intramolecular Aminoiodination of Alkynes

  • 0615

    Enantioenriched Tetrahydropyridines from Racemic Allyltriflamides through Kinetic Resolution

  • 0616

    Synthesis of Triarylethanes by 1,6-Conjugate Addition

  • 0617

    Synthesis of Azacycles through a 1,2-Metalate Shift

  • 0618

    General Solid-Phase Protocol for Modular Oligonucleotide Synthesis

  • 0619

    Multigram Electrosynthesis of Enecarbamates and Related Building Blocks

  • 0620

    Indolylcyclopentenes through an Enantioselective Aminopalladation–Heck Reaction

  • 0621

    Synthesis of Enantiopure Piperidines by an Asymmetric Aza-Prins Reaction

  • 0622

    5-(Trifluoromethyl)pyrazoles by a Regioselective [3+2] Cycloaddition

  • 0623

    Trityl-Cation-Initiated Cycloaddition of Benzyl-Substituted Vinylcyclopropanes with Hydrosilanes

  • 0624

    Protein-Templated Assembly of Heterodimeric Tryptase Inhibitors

  • 0625

    Generation and Regioselective 3,4-Difunctionalization of Pyridynes

  • 0626

    Protecting-Group-Free Asymmetric Synthesis of Pyroglutamic Acid Esters

  • 0627

    Disaccharide Synthesis through Regioselective O-Glycosylation under Boronic Acid Catalysis

    • Synthesis of Materials and Unnatural Products

  • z0629

    All PDFs of this category

  • 0629

    Short and Sweet: A New Synthetic Route to Acepleiadylene

  • 0630

    Twist and Lock: Helicene–Boranil Fluorophores

  • 0631

    Lights, Dienophile, Action!

  • 0632

    A Distorted Hybrid Corannulene–Dibenzobistetracene

  • 0633

    Polyisobutene Oxidation by Ruthenium Catalysis

  • 0634

    Unnatural α-Amino Acid Derivative Synthesis

  • 0635

    Easy Access to Chiral Siloxanes and Alkoxysilanes

  • 0636

    New Azahelicenes by Cross-Coupling

  • 0637

    Put a 1,3,5,2,4-Oxadiazadiborinan Ring on It

  • 0638

    Unsymmetrical Thiophene-Based [7]Helicenes

  • 0639

    Synthesis of Conjugated Polymers by Palladium-Catalyzed Oxidative Aromatic Homocoupling

  • 0640

    Synthesis of Poly(Digermene) by Ge=Ge Metathesis

    • Metals in Synthesis

  • z0641

    All PDFs of this category

  • 0641

    Synthesis of Hydrazides by N–N Coupling

  • 0642

    Regio- and Enantioselective Copper-Catalyzed Hydrocarboxylation of Allenes

  • 0643

    Enantioselective C–H Rutheniation for the Preparation of Tetrahydrocarbazoles and Cyclohepta[b]indoles

  • 0644

    Nickel-Catalyzed Cyanation of (Hetero)arenes

  • 0645

    Radical 1,2-Additions to Alkenes and Alkynes

  • 0646

    Regiodivergent [3+2] and [3+3] Annulations by Cooperative N‑Heterocyclic Carbene/Iridium Catalysis

  • 0647

    Synthesis of Axially Chiral Diamines by Atroposelective Transfer Hydrogenation

  • 0648

    Three-Component Asymmetric β-Lactam Synthesis via a Cu/Pd-Catalyzed Interrupted Kinugasa Allylic Alkylation

  • 0649

    Enantioselective Zinc-Catalyzed Conjugate Addition of Catalytically Generated Homoenolates

  • 0650

    Nickel-Catalyzed Alyklborylation via an Alkenylboration Hydrogenation Sequence

  • 0651

    Radical Decarboxylative Fluorination of Aromatic Carboxylic Acids

  • 0652

    Solid-State Suzuki–Miyaura Cross-Coupling of Insoluble Aryl Halides Using a Ball-Milling Approach

  • 0653

    Nickel-Catalyzed Enantioselective α-Alkenylation of N-Sulfonyl Amines

  • 0654

    Manganese-Catalyzed Electrooxidative C–H/P–H Cross-Coupling

  • 0655

    Synthesis of Bicyclopentane-Containing Chiral Alcohols

  • 0656

    Copper-Catalyzed Regioselective Asymmetric Addition of 1,4-Pentadienes to Ketones

  • 0657

    Asymmetric Reductive Cross-Coupling of Aryl Iodides with α-Chloroboranes by Nickel/Photoredox Catalysis

  • 0658

    Palladium-Catalyzed ortho-C–H Functionalization of Aromatic Ketones for Site-Selective Fluorination

  • 0659

    1,2-Metalate Rearrangement of Boronates via Iridium-Catalyzed Allylation

  • 0660

    Coupling of Bis(perfluoroalkyl)zinc with Alkynyl Bromides

  • 0661

    Stereoselective Synthesis of Tetrasubstituted Monofluoroalkenes from gem-Difluoroalkenes

  • 0662

    One-Carbon Homologation of Alkyl Iodides for the Synthesis of gem-Diborylalkanes via Copper Catalysis

  • 0663

    Iridium-Catalyzed Enantioselective C–C Coupling of Ethanol with Allylic Acetates

  • 0664

    Hydroboration of Alkynes and Alkenes

  • 0665

    Preparation of Homoallenyl Alcohols

  • 0666

    Asymmetric Photocatalyzed Functionalization of Acrylates

  • 0667

    Enantioselective Carbocyanation of Alkenes by Copper/Photoredox Dual Catalysis

  • 0668

    ortho-Homoallylation of Aromatic Ketones

  • 0669

    Nagata Hydrocyanation: Synthesis of β-Cyanoketones

    • Polymer-Supported Synthesis

  • z0671

    All PDFs of this category

  • 0671

    Photocatalytic Functionalization of Alkenes with a Metal–Organic Layer Containing Eosin Y and Iron

  • 0672

    Continuous-Flow Asymmetric Aldol Reaction with a Polystyrene-Supported Prolinamide Organocatalyst

  • 0673

    The Suzuki–Miyaura Coupling on Magnesium Organosilicate-Supported Palladium Nanoparticles

  • 0674

    Decarboxylation and Decarboxylative Arylation of Carboxylic Acid on Boron Carbon Nitrides

  • 0675

    Synthesis of Anilines from Cyclohexanes and Ammonium Acetate with a Pd/C–Ethylene System

  • 0676

    Palladium-Free Suzuki–Miyaura Coupling with a Bismuth-Based Composite Photocatalyst

  • 0677

    Stabilized-Iridium-Nanoparticle-Catalyzed Cross-β-Alkylation of Primary Alcohols

  • 0678

    Synthesis of α-Diketones with a Bifunctional Iron Nanocomposite Catalyst

  • 0679

    C−H Arylation of Heteroarenes by Ni(II) Supported on a Bipyridine-Containing Porous Macroligand

  • 0680

    Synthesis of 3,4-Dihydropyrimidinones with a Magnetite Nanoparticle-Immobilized Acidic Ionic Liquid

  • 0681

    Mizoroki–Heck Reaction in Water Catalyzed by Pd(t-Bu3P)2-Containing Nanoparticles Derived from FeCl3

    • Organo- and Biocatalysis

  • z0683

    All PDFs of this category

  • 0683

    Enantioselective Minisci-Reaction of N-Heterocycles and Amides through Hydrogen-Atom Transfer

  • 0684

    Chiral Phosphoric Acid-Catalyzed Desymmetrization of 1,3-Diones by Using Arylhydrazines

  • 0685

    Pyrimidopteridine-Catalyzed Photoredox Olefin Hydroamination

  • 0686

    Highly para-Selective Hydroarylation of Phenols with 1,3-Dienes

  • 0687

    β-Functionalization of Saturated Aza-Heterocycles: A Two-Step Organic Photoredox Catalysis Approach

  • 0688

    Photoredox-Catalyzed Redox-Neutral Synthesis of Densely Functionalized Pyrroles

  • 0689

    Peptide-Catalyzed Regioselective Acylation of Carbohydrates

  • 0690

    Rational Site-Directed Mutagenesis of a Diels–Alderase Permits Reversal of Diastereoselectivity

  • 0691

    NHC-Catalyzed Asymmetric Stetter-Aldol-Sequence Grants Access to Axially Chiral N-Aryl Succinimides

  • 0692

    Lewis Base-Catalyzed Thioarylation of Cinnamyl Amines with Phenols

    • Chemistry in Medicine and Biology

  • z0693

    All PDFs of this category

  • 0693

    Seven-Step Synthesis of (–)-Colchicine

  • 0694

    Better Photoswitch, Better Photopharmacology

  • 0695

    Shocking Selectivity for Hsp90α

  • 0696

    Concise Synthesis of the Novel Spliceosome Inhibitor H3B-8800

  • 0697

    A Blood-Brain Barrier Penetrant Photooxygenation Catalyst for Aβ Degradation

  • 0698

    A Novel APJ Receptor Agonist through SAR Studies

  • 0699

    Photocaged Antibiotics

  • 0700

    Uncaging Ligands using Bioluminolysis

  • 0701

    A Better Version of Rhodamine Voltage Reporter by ‘Trapping‘

  • 0702

    Thermal Proteome Profiling Identifies the Target of Indophagolin

  • 0703

    Covalent Suppression of the Cellular HDM2/p53 Protein-Protein Interaction using NASA

  • 0704

    Late-Stage Radiolabeling Enabled by SuFEx

  • 0705

    The Woodwardian Synthesis of Erythromycin A

    • Peptide Chemistry

  • z0707

    All PDFs of this category

  • 0707

    Manganese-Catalyzed Late-Stage Functionalization of Peptides

  • 0708

    Iodine-Catalyzed Oxidative 2-Selenylation of Tryptophans

  • 0709

    Synthesis of β2-Amino Acid Derivatives by Aminomethylation of Arylacetic Acid Esters

  • 0710

    Tetrabutylammonium Decatungstate-Catalyzed Synthesis of γ-Carbonyl α-Amino Acids

  • 0711

    Photoredox-Catalyzed Radical Addition to Glyoxylate-Derived N-Sulfinyl Imines

  • 0712

    Phospha-Michael Addition to Access β-Phosphorus-Containing α-Amino Acids

  • 0713

    Phosphate-Reagent-Mediated Peptide Coupling Reactions

  • 0714

    N-Arylation of Amino Acids without Using Transition Metal Catalysts

    • Flow Chemistry

  • z0715

    All PDFs of this category

  • 0715

    Synthesis of [1.1.1]Propellane and Subsequent Functionalization in Continuous-Flow Processes

  • 0716

    Synthesis of Indolo[2,1-a]isoquinoline Derivatives under Visible-Light Irradiation in Flow

  • 0717

    Superacid and Flow Chemistry Approach towards Ferrier Rearrangement

  • 0718

    Synthesis of Glyoxal Derivatives in Continuous Flow

  • 0719

    Electrochemical Aza-Wacker Cyclization in Flow