DOI: 10.1055/s-00035024

Thrombosis and Haemostasis

Ausgabe 07 · Volume 112 · 2014 DOI: 10.1055/s-008-36060

Invited Editorial Focus

1
Potpara, Tatjana S.; Lane, Deirdre A.: Diving to the foot of an iceberg: The SEARCH for undiagnosed atrial fibrillation

Current Controversies

4
Serebruany, Victor L.; Fortmann, Seth D.: Viewpoint: “Underutilisation of novel antiplatelet agents – myths, generics, and economics”
10
Sibbing, Dirk; Massberg, Steffen: There’s life in the old dog yet: Clopidogrel competing with prasugrel and ticagrelor for treatment of ACS patients
12
Wallentin, Lars; Himmelmann, Anders; Storey, Robert F.; Steg, Philippe Gabriel; Harrington, Robert A.; for the PLATO Publications Committee: Utilisation of novel anti-platelet agents: evidence, guidelines and proven patients’ value

T&H Insight

15
Maegdefessel, Lars: Micro-effects of smoking in cardiovascular disease aetiology

Review Article

16
Aronson, Doron: Subgroup analyses with special reference to the effect of antiplatelet agents in acute coronary syndromes
26
Gawaz, Meinrad; Vogel, Sebastian; Pfannenberg, Christina; Pichler, Bernd; Langer, Harald; Bigalke, Boris: Implications of glycoprotein VI for theranostics
32
Undas, Anetta: Fibrin clot properties and their modulation in thrombotic disorders

Blood Coagulation, Fibrinolysis and Cellular Haemostasis

43
Wakabayashi, Hironao; Wintermute, Jennifer M.; Fay, Philip J.: Combining mutations that modulate inter-subunit interactions and proteolytic inactivation enhance the stability of factor VIIIa
53
Brandt, Sven; Krauel, Krystin; Gottschalk, Kay E.; Renné, Thomas; Helm, Christiane A.; Greinacher, Andreas; Block, Stephan: Characterisation of the conformational changes in platelet factor 4 induced by polyanions: towards in vitro prediction of antigenicity
Zusatzmaterial
65
Álvarez Román, María Teresa; Bello, Ihosvany Fernández; Arias-Salgado, Elena G.; Pollmar, María Isabel Rivas; Yuste, Víctor Jiménez; Salces, Mónica Martín; Butta, Nora V.: Effects of thrombopoietin receptor agonists on procoagulant state in patients with immune thrombocytopenia
73
Petersen, Jesper Friis; Bergholt, Thomas; Nielsen, Anne Kristine; Paidas, Michael J.; Løkkegaard, Ellen Christine L.: Combined hormonal contraception and risk of venous thromboembolism within the first year following pregnancy
79
Yau, Jonathan W.; Liao, Peng; Fredenburgh, James C.; Roberts, Robin S.; Weitz, Jeffrey I.: Only high levels of dabigatran attenuate catheter thrombosis in vitro and in rabbits
87
Martinez-Pinna, Roxana; Lindholt, Jes S.; Madrigal-Matute, Julio; Blanco-Colio, Luis M.; Esteban-Salan, Margarita; Torres-Fonseca, Monica Maria; Lefebvre, Thibault; Delbosc, Sandrine; Laustsen, Jesper; Driss, Fathi; de Ceniga, Melina Vega; Gouya, Laurent; Weiss, Günter; Egido, Jesus; Meilhac, Olivier; Michel, Jean-Baptiste; Martin-Ventura, Jose L.: From tissue iron retention to low systemic haemoglobin levels, new pathophysiological biomarkers of human abdominal aortic aneurysm
Zusatzmaterial
96
Brehm, Maria A.; Huck, Volker; Aponte-Santamaría, Camilo; Obser, Tobias; Grässle, Sandra; Oyen, Florian; Budde, Ulrich; Schneppenheim, Sonja; Baldauf, Carsten; Gräter, Frauke; Schneider, Stefan W.; Schneppenheim, Reinhard: von Willebrand disease type 2A phenotypes IIC, IID and IIE: A day in the life of shear-stressed mutant von Willebrand factor
Zusatzmaterial
109
Solomon, Cristina; Baryshnikova, Ekaterina; Tripodi, Armando; Schlimp, Christoph J.; Schöchl, Herbert; Cadamuro, Janne; Winstedt, Dag; Asmis, Lars; Ranucci, Marco: Fibrinogen measurement in cardiac surgery with cardiopulmonary bypass: Analysis of repeatability and agreement of Clauss method within and between six different laboratories
Zusatzmaterial

Platelets and Blood Cells

118
Cavalca, Viviana; Rocca, Bianca; Squellerio, Isabella; Dragani, Alfredo; Veglia, Fabrizio; Pagliaccia, Francesca; Porro, Benedetta; Barbieri, Silvia Stella; Tremoli, Elena; Patrono, Carlo: In vivo prostacyclin biosynthesis and effects of different aspirin regimens in patients with essential thrombocythaemia
128
Badrnya, Sigrun; Baumgartner, Roland; Assinger, Alice: Smoking alters circulating plasma microvesicle pattern and microRNA signatures
Zusatzmaterial
137
Asher, Elad; Fefer, Paul; Shechter, Michael; Beigel, Roy; Varon, David; Shenkman, Boris; Savion, Naphtali; Hod, Hanoch; Matetzky, Shlomi: Increased mean platelet volume is associated with non-responsiveness to clopidogrel
142
Huang, Zhangsen; Liu, Pu; Zhu, Linjing; Li, Nailin; Hu, Hu: P2X1-initiated p38 signalling enhances thromboxane A2-induced platelet secretion and aggregation

Endothelium and Vascular Development

151
Liu, Hui; Devraj, Kavi; Möller, Kerstin; Liebner, Stefan; Hecker, Markus; Korff, Thomas: EphrinB-mediated reverse signalling controls junctional integrity and pro-inflammatory differentiation of endothelial cells

Cardiovascular Biology and Cell Signalling

164
Yang, Likui; Dinarvand, Peyman; Qureshi, Shabir H.; Rezaie, Alireza R.: Engineering D-helix of antithrombin in alpha-1-proteinase inhibitor confers antiinflammatory properties on the chimeric serpin
176
Adlbrecht, Christopher; Wurm, Raphael; Humenberger, Michael; Andreas, Martin; Redwan, Bassam; Distelmaier, Klaus; Klappacher, Günter; Lang, Irene M.: Peri-interventional endothelin-A receptor blockade improves long-term outcome in patients with ST-elevation acute myocardial infarction
183
Wild, Johannes; Soehnlein, Oliver; Dietel, Barbara; Urschel, Katharina; Garlichs, Christoph D.; Cicha, Iwona: Rubbing salt into wounded endothelium: Sodium potentiates proatherogenic effects of TNF-α under non-uniform shear stress
196
Cesari, Francesca; Marcucci, Rossella; Gori, Anna Maria; Burgisser, Costanza; Francini, Sara; Roberts, Anna Teresa; Sofi, Francesco; Gensini, Gian Franco; Abbate, Rosanna; Fattirolli, Francesco: Adherence to lifestyle modifications after a cardiac rehabilitation program and endothelial progenitor cells

New Technologies, Diagnostic Tools and Drugs

205
Balasubramaniam, Karthik; Viswanathan, Girish; Dragone, Jeff; Grose-Hodge, Rachael; Martin, Patrick; Troy, Steve; Preston, Peter; Zaman, Azfar G.: Antithrombotic properties of rafigrelide: a phase 1, open-label, non-randomised, single-sequence, crossover study
Zusatzmaterial

Letters to the Editor

216
Cheng, Xian Wu; Sasaki, Takeshi; Kuzuya, Masafumi: The role of cysteinyl cathepsins in venous disorders
219
Stephan, Femke; Bulder, Ingrid; Luken, Brenda M.; Hazelzet, Jan; Wuillemin, Walter A.; Zeerleder, Sacha: Complexes of factor VII-activating protease with plasminogen activator inhibitor-1 in human sepsis