DOI : 10.1055/s-00000094

Zeitschrift für Gastroenterologie

Issue 12 · Volume 53 · December 2015 DOI: 10.1055/s-005-30542


32. Jahrestagung der Deutschen Arbeitsgemeinschaft zum Studium der Leber
Düsseldorf, 22. – 23. Januar 2016

Kongresspräsident: Prof. Dr. Dieter Häussinger
Abstracts (HTML) List of Authors
A1_1
Ghallab, A; Reif, R; Hassan, R; Seddek, A; Hengstler, JG: Intravital real time imaging of liver damage and regeneration by functional two-photon microscopy
A1_2
Klein, S; Reul, WH; Schierwagen, R; Uschner, FE; Strassburg, CP; Walther, T; Trebicka, J: Neprilysin controls the switch between hepatic vasoconstriction and fibrogenesis
A1_3
Bangen, JM; Hammerich, L; Tacke, F; Trautwein, C; Liedtke, C: Targeting liver fibrosis by siRNA-mediated inhibition of Cyclin E1 in mice
A1_4
Beuke, K; Schildberg, F; Pinna, F; Albrecht, U; Liebe, R; Bissinger, M; Schirmacher, P; Dooley, S; Bode, J; Knolle, P; Kummer, U; Sahle, S; Breuhahn, K: A computational multi-scale model for the integration of paracrine stimuli activating NF-kB signalling in hepatocytes after lipopolysaccharide (LPS) treatment
A1_5
Müller, M; Wetzel, S; Köhn-Gaone, J; Chalupsky, K; Lüllmann-Rauch, R; Barikbin, R; Wöhner, B; Tiegs, G; Rose-John, S; Sedlacek, R; Tirnitz-Parker, JEE; Saftig, P; Schmidt-Arras, D: A disintegrin and metalloprotease 10 (ADAM10) is a central regulator of liver tissue homeostasis
A1_6
Wewering, F; Jouy, F; Wissenbach, DKWK; Gebauer, S; Bergen, M von; Luch, A; Kalkhof, S; Zellmer, S: A human hepatic in vitro co-culture system for the analysis of DILI related signaling
A1_7
Glaser, F; Engel, B; John, C; Krech, T; Carambia, A; Herkel, J; Lohse, AW; Heeren, J; Schramm, C; Schwinge, D: A new mouse model of sclerosing cholangitis combining toxic and immune mediated bile duct injury
A1_8
Kordes, C; Sawitza, I; Götze, S; Häussinger, D: Beyond fibrosis: stellate cells as liver stem cells
A1_9
Bowe, A; Hoffmann, V; Morten, CH; Fickert, P; Nierhoff, D: Cholestasis induces expression of the oncofetal marker Nope in adult murine liver independent of Fxr
A1_10
Ehlting, C; Sanwald, J; Albrecht, U; Deenen, R; Köhrer, K; Gaestel, M; Feuer, R; Sawodny, O; Häussinger, D; Bode, JG: Crucial role of the interplay of the MAPKAP kinases 2 and 3 for LPS-induced inflammation and their relevance for liver pathogenesis
A1_11
Schneider, F; Churin, Y; Köppel, A; Baier, KM; Tschuschner, A; Roderfeld, M; Roeb, E: Das synthetische Chaperon 4-PBA induziert eine Akut-Phase-Reaktion im Maus-Modell für Protein-Speicherkrankheiten
A1_12
Pütter, L; Campos, G; Rochlitz, K; Dahmen, U; Hengstler, JG; Godoy, P: Deletion of WISP1 leads to higher sensitivity to carbon tetrachloride-induced liver damage
A1_13
Dewidar, B; Shen, Z; Li, Y; Dooley, S; Weng, HL: Delta like ligand4 modulates chemokine ligand 2 through impacting the NFkB pathway
A1_14
Hollenbach, M; Thonig, A; Pohl, S; Ripoll, C; Greinert, R; Michl, P; Zipprich, A: Die Hemmung der Glyoxalase-I durch Ethylpyruvat vermindert den LPS-induzierten Anstieg des portalen Drucks
A1_15
Roderburg, C; Roy, S; Benz, F; Tacke, F; Neumann, UP; Trautwein, C; Luedde, T: Die Repression von miR-192 schützt vor hepatischer Ischämie/Reperfusionsschädigung
A1_16
Görtzen, J; Bierwolf, J; Klein, S; Schierwagen, R; Strassburg, CP; Laleman, W; Pollok, JM; Wells, RG; Trebicka, J: Differential activation of RhoA and c-SRC in experimental and human fibrosis
A1_17
Benz, F; Roderburg, C; Roy, S; Tacke, F; Neumann, UP; Trautwein, C; Luedde, T: Ein zellspezifisches Netzwerk TGF-beta abhängiger micro-RNAs reguliert organübergreifende Prozesse in der Fibrogenese
A1_18
Schumacher, EC; Götze, S; Kordes, C; Häussinger, D: Epigenetic changes contribute to hepatic stellate cell activation
A1_19
Maass, T; Itzel, T; Kanzler, S; Teufel, A: Erhöhte Mortalität durch leberspezifische Koexpression der profibrogenetischen Faktoren PDGF-B und TGF-b
A1_20
Nakhaei-Rad, S; Nakhaeizadeh, H; Götze, S; Kordes, C; Häussinger, D; Ahmadian, MR: Expression, epigenetical regulation and signaling network of embryonic stem cell-expressed RAS in hepatic stellate cells
A1_21
Giebeler, A; Brandenburg, LO; Wang, JM; Neumann, U: FPR1 might play a relevant role in prevention of liver fibrosis
A1_22
Asimakopoulou, A; Fülöp, A; Borkham-Kamphorst, E; Gassler, N; Berger, T; Mak, TW; Hopf, C; Henkel, C; Weiskirchen, R: Hepatic Proteome and Lipid Profiling of Wild Type and Lipocalin-2-Deficient Mice in Experimental Steatosis
A1_23
Pfaff, M; Neumann, K; Karimi, K; Tiegs, G: Hepatocyte dependent induction of regulatory T-cell subsets
A1_24
Wolf, A; Schreier, B; Hammer, S; Pohl, S; Gekle, M; Zipprich, A: Hypoxia and inflammation reduce the expression of the mineralocorticoid receptor (MR) in the hepatocytes – a mechanism that explains the lower expression of MR in cirrhosis
A1_25
Campos, G; Schmidt-Heck, W; Widera, A; Rochlitz, K; Leserer, S; Pütter, L; Ghallab, A; Hengstler, J; Godoy, P: Identification of transcriptional regulatory networks in acute liver damage and regeneration
A1_26
Freese, K; Dorn, C; Thasler, WE; Müller, M; Hellerbrand, C: Increased expression of histone deacetylase 7 during hepatic stellate cell activation promotes pro-fibrogenic gene expression
A1_27
Schiller, B; Wegscheid, C; Horst, AK; Tiegs, G: Influence of the microbiome in regulating ConA-induced-liver injury
A1_28
Lambertz, J; Boaru, SG; Borkham-Kamphorst, E; Weiskirchen, R: Lipocalin 2 und Perilipin 5 in der Pathogenese der durch Fruktose ausgelösten NAFLD
A1_29
Liebe, R; Meyer, C; Chen, S; Wan, F; Abramovic, K; Müller, A; Gaitantzi, H; König, C; Augustin, H; Ebert, M; Dooley, S; Breitkopf-Heinlein, K: LPS and bone morphogenetic protein (BMP)-9 regulate the hepatocytes acute phase response by affecting hepatic stellate cells
A1_30
Meurer, SK; Neß, M; Weiskirchen, R: Mast cells inhibit activation and profibrogenic activities of hepatic stellate cells
A1_31
Neß, M; Bangen, JM; Huber, M; Liedtke, C; Weiskirchen, R; Meurer, SK: Regulation and profibrogenic effects of TGF-β1 signaling in mast cells, a cell type contributing to the outcome of hepatic injury
A1_32
Borkham-Kamphorst, E; Steffen, BT; Van de Leur, E; Haas, U; Tihaa, L; Weiskirchen, R: Overwhelming high quantities of the matricellular protein CCN1/CYR61 induce ER stress-related cellular apoptosis in hepatic stellate cells
A1_33
Nguyen, HTT; Huynh, KC; Stoldt, VR; Scharf, RE: Platelet integrin-dependent fibrillogenesis of fibronectin: Impact of shear stress
A1_34
Bartneck, M; Fech, V; Trautwein, C; Tacke, F: Promotion of macrophage activation and inflammation in chronic liver disease by the histidine-rich glycoprotein
A1_35
Hall, RA; Lammert, F: Multiple quantitative trait loci modeling (MQM) of hepatic fibrosis in a murine intercross
A1_36
Huynh, KC; Nguyen, H; Stoldt, V; Scharf, RE: Shear-induced fibrillar-like supramolecule of plasma fibronectin: A new form of fibronectin with enhanced activity in platelet adhesion and aggregation
A1_37
Stoldt, VR; Nguyen, HTT; Scharf, RE: Shear-related fibrillogenesis of fibronectin
A1_38
Su, J; Gan-Schreier, H; Chamulitrat, W; Stremmel, W; Pathil, A: The bile acid-phospholipid conjugate Ursodeoxycholyl Lysophosphatidylethanolamide (UDCA-LPE) disturbs pro-fibrogenic Integrin and TGFβ signaling
A1_39
Spomer, L; Höhne, J; Hov, J; Karlsen, T; Nierhoff, D; Häussinger, D; Keitel, V: The TGR5 protein amount is reduced in patients with primary sclerosing cholangitis (PSC)
A1_40
Widera, AB; Pütter, L; Leserer, S; Campos, G; Rochlitz, K; Reif, R; Hammad, S; Ghallab, AG; Marchan, R; Hengstler, JG; Godoy, PG: WISP1 modulates immune cell infiltration upon drug-induced liver injury (DILI)
A1_41
Helmrich, NL; Churin, Y; Tschuschner, A; Roderfeld, M; Roeb, E: Therapeutische Effekte der Modulation des Endocannabinoid-Rezeptor Signalwegs
A1_42
Tsay, HC; Yuan, Q; Balakrishnan, A; Manns, MP; Ott, M; Deep Sharma, A: MicroRNA-221 inhibition in hepatocytes ameliorates liver fibrosis