DOI: 10.1055/s-00000025

Hormone and Metabolic Research

Issue 09 · Volume 28 · September 1996 DOI: 10.1055/s-002-6641

Introduction

403
Matthews, David R.; Riddle, Matthew C.: Introduction

Overview

404
Gerich, J. E.: Pathogenesis and Treatment of Type 2 (Noninsulin-Dependent) Diabetes Mellitus (NIDDM)

Clinical

413
Schneider, J.: An Overview of the Safety and Tolerance of Glimepiride
419
Draeger, K. E.; Wernicke-Panten, K.; Lomp, H.-J.; Schüler, E.; Roßkamp, R.: Long-Term Treatment of Type 2 Diabetic Patients with the New Oral Antidiabetic Agent Glimepiride (Amaryl®): A Double-Blind Comparison with Glibenclamide
426
Dills, Diana G.; Schneider, Jill; The Glimepiride/Glyburide Research Group: Clinical Evaluation of Glimepiride versus Glyburide in NIDDM in a Double-Blind Comparative Study
430
Riddle, M. C.: Combined Therapy With a Sulfonylurea Plus Evening Insulin: Safe, Reliable, and Becoming Routine
434
Rosenkranz, B.: Pharmacokinetic Basis for the Safety of Glimepiride in Risk Groups of NIDDM Patients

Tissue Sensitivity

440
Karam, J. H.: Reversible Insulin Resistance in Non-Insulin-Dependent Diabetes Mellitus
445
Clark, H. E.; Matthews, D. R.: The Effect of Glimepiride on Pancreatic β-Cell Function Under Hyperglycaemic Clamp and Hyperinsulinaemic, Euglycaemic Clamp Conditions in Non-Insulin-Dependent Diabetes Mellitus
451
Massi-Benedetti, M.; Herz, M.; Pfeiffer, Claudia: The Effects of Acute Exercise on Metabolic Control in Type II Diabetic Patients Treated with Glimepiride or Glibenclamide

Mechanisms

456
Ashcroft, Frances M.: Mechanisms of the Glycaemic Effects of Sulfonylureas
464
Kramer, W.; Müller, G.; Geisen, K.: Characterization of the Molecular Mode of Action of the Sulfonylurea, Glimepiride, at β-Cells
469
Müller, G.; Geisen, K.: Characterization of the Molecular Mode of Action of the Sulfonylurea, Glimepiride, at Adipocytes
488
Lazdunski, M.: Ion Channel Effects of Antidiabetic Sulfonylureas

CV-Effect

496
Geisen, K.; Végh, Agnes; Krause, E.; Papp, J. C.: Cardiovascular Effects of Conventional Sulfonylureas and Glimepiride
508
Eckel, J.: Direct Effects of Glimepiride on Protein Expression of Cardiac Glucose Transporters
512
Bijlstra, P. J.; Russel, F. G. M.; Thien, T.; Lutterman, J. A.; Smits, P.: Effects of Tolbutamide on Vascular ATP-Sensitive Potassium Channels in Humans

Debate

517
Waldhäusl, W.: Role of Sulfonylureas in Non-Insulin-Dependent Diabetes Mellitus: Part I - “The pros”
522
Heine, R. J.: Role of Sulfonylureas in Non-Insulin-Dependent Diabetes Mellitus: Part II - “The cons”