DOI: 10.1055/s-00000077

Seminars in Thrombosis and Hemostasis

Issue S 1 · Volume 32 · February 2006 DOI: 10.1055/s-002-4849 Thrombin Biology in the 21st Century: Implications in Hemostasis, Inflammation, Coagulopathies, and Cancer Harold R Roberts M.D. Earl W Davie Ph.D.

PREFACE

  • 001
    Roberts, Harold R.; Davie, Earl W.:

    Thrombin Biology in the 21st Century

  • 003
    Davie, Earl W.; Kulman, John D.:

    An Overview of the Structure and Function of Thrombin

  • 016
    Bode, Wolfram:

    The Structure of Thrombin: A Janus-Headed Proteinase

  • 032
    Roberts, Harold R.; Hoffman, Maureane; Monroe, Dougald M.:

    A Cell-Based Model of Thrombin Generation

  • 039
    Bunnett, Nigel W.:

    Protease-Activated Receptors: How Proteases Signal to Cells to Cause Inflammation and Pain

  • 049
    Esmon, Charles T.:

    Inflammation and the Activated Protein C Anticoagulant Pathway

  • 061
    Ruf, Wolfram; Mueller, Barbara M.:

    Thrombin Generation and the Pathogenesis of Cancer

  • 069
    Möller, Thomas; Weinstein, Jonathan R.; Hanisch, Uwe-Karsten:

    Activation of Microglial Cells by Thrombin: Past, Present, and Future

  • 077
    Hedner, Ulla:

    Mechanism of Action of Factor VIIa in the Treatment of Coagulopathies

  • 086
    Bishop, Paul D.; Lewis, Kenneth B.; Schultz, Jody; Walker, Kathleen M.:

    Comparison of Recombinant Human Thrombin and Plasma-Derived Human α-Thrombin

  • 098
    Lawson, Jeffrey H.:

    The Clinical Use and Immunologic Impact of Thrombin in Surgery