DOI: 10.1055/s-00000077

Seminars in Thrombosis and Hemostasis

Issue 01 · Volume 38 · February 2012 DOI: 10.1055/s-002-22787 Hot Topics III Guest Editor, Emmanuel J. Favaloro, Ph.D., M.A.I.M.S., F.F.Sc. (RCPA)

Preface

01
Favaloro, Emmanuel J.: Hot Topics III

Editorial–Welcome 2012

05
Favaloro, Emmanuel J.: Welcome to Seminars in Thrombosis & Hemostasis 2012

07
Schulman, Sam; Majeed, Ammar: The Oral Thrombin Inhibitor Dabigatran: Strengths and Weaknesses
16
Harenberg, Job; Giese, Christina; Marx, Svetlana; Krämer, Roland: Determination of Dabigatran in Human Plasma Samples
23
Salmela, Birgitta; Joutsi-Korhonen, Lotta; Armstrong, Elina; Lassila, Riitta: Active Online Assessment of Patients Using New Oral Anticoagulants: Bleeding Risk, Compliance, and Coagulation Analysis
31
Cuker, Adam: Current and Emerging Therapeutics for Heparin-Induced Thrombocytopenia
38
Turner, Nancy; Nolasco, Leticia; Moake, Joel: Generation and Breakdown of Soluble Ultralarge von Willebrand Factor Multimers
47
Chapman, Kent; Seldon, Michael; Richards, Ross: Thrombotic Microangiopathies, Thrombotic Thrombocytopenic Purpura, and ADAMTS-13
55
Szántó, Tímea; Joutsi-Korhonen, Lotta; Deckmyn, Hans; Lassila, Riitta: New Insights into von Willebrand Disease and Platelet Function
64
Jayandharan, Giridhara Rao; Srivastava, Arun; Srivastava, Alok: Role of Molecular Genetics in Hemophilia: From Diagnosis to Therapy
79
Coppola, Antonio; Tagliaferri, Annarita; Di Capua, Mirko; Franchini, Massimo: Prophylaxis in Children with Hemophilia: Evidence-Based Achievements, Old and New Challenges
95
Franchini, Massimo; Mannucci, Pier Mannuccio: Thrombin and Cancer: From Molecular Basis to Therapeutic Implications
102
Aatonen, Maria; Grönholm, Mikaela; Siljander, Pia R.-M.: Platelet-Derived Microvesicles: Multitalented Participants in Intercellular Communication
114
Targher, Giovanni; Pichiri, Isabella; Lippi, Giuseppe: Vitamin D, Thrombosis, and Hemostasis: More than Skin Deep