DOI: 10.1055/s-00000077

Seminars in Thrombosis and Hemostasis

Issue S 01 · Volume 34 · October 2008 DOI: 10.1055/s-002-13710 Landmarks in Anti-Thrombin Drug Development: The Argatroban Story Jeanine M Walenga Ph.D. Henri Bounameaux M.D. Yasuo Ikeda M.D.

PREFACE

  • 001
    Walenga, Jeanine M.; Bounameaux, Henri; Ikeda, Yasuo:

    Landmarks in Anti-Thrombin Drug Development: The Argatroban Story

  • 003
    Markwardt, Fritz:

    FOREWORD

  • 005
    Fareed, Jawed; Walenga, Jeanine M.:

    A Tribute to Professor Hans Klaus Breddin

  • 007
    Ikeda, Yasuo; Wanaka, Keiko; Okamoto, Utako:

    Okamoto's Strategy to Develop Argatroban: An Innovative Concept for the Future

  • 012
    Bounameaux, Henri:

    Overview of Direct Thrombin Inhibitors in Clinical Practice

  • 018
    Vissac, Anne Marie; Amiral, Jean:

    Mechanisms Involved in Heparin-Induced Thrombocytopenia and Associated Thrombosis

  • 027
    Gruel, Yves; Pouplard, Claire:

    Overview of Heparin-Induced Thrombocytopenia. Diagnosis and Treatment in Europe with an Emphasis on France

  • 037
    Miyata, Shigeki; Yamamoto, Haruko; Kamei, Masataka; Nakatani, Takeshi; Kobayashi, Junjiro; Tsuji, Tetsu; Minematsu, Kazuo; Tomoike, Hitonobu:

    Heparin-Induced Thrombocytopenia Clinical Studies and the Efficacy of Argatroban in Japan

  • 048
    Dempfle, Carl-Erik:

    Clinical Experience of Argatroban in Germany

  • 052
    Koster, Andreas; Fischer, Karl-Georg:

    Argatroban Anticoagulation in Patients following Cardiovascular Surgery and in ICU Patients with and without Renal-Replacement Therapy

  • 056
    Matsuo, Takefumi; Wanaka, Keiko:

    Hemodialysis and Argatroban

  • 062
    Iqbal, Omer; Adiguzel, Cafer; Lewis, Bruce E.; Cunanan, Josephine; Fareed, Jawed:

    Argatroban for Percutaneous Coronary Interventions

  • 075
    Harder, Sebastian; Koster, Andreas; Klinkhardt, Ute:

    The Direct Thrombin Inhibitor Argatroban: A Review of Its Pharmacokinetics and Pharmacokinetic/Pharmacodynamic Relationships

  • 081
    Nowak, Götz; Lange, Ute; Bucha, Elke:

    Drug Monitoring of Argatroban Using the Ecarin Chromogenic Assay

  • 087
    Samama, Meyer Michel; Le Flem, Léna; Guinet, Céline; Depasse, François:

    Effect of Argatroban versus Recombinant Hirudin on Tissue-Factor-Mediated Thrombin Generation: An in Vitro Study

  • 091
    He, Shu; Wallen, Håkan; Johnsson, Hans; Blombäck, Margareta:

    In Vitro Effects of Argatroban, Lepirudin, Bivalirudin, and Danaparoid on Fibrin Gel Permeability

  • 097
    Hoppensteadt, Debra A.; Jeske, Walter; Walenga, Jeanine M.; Bick, Rodger L.; Fareed, Jawed:

    The Anti-Inflammatory Effects of Argatroban Can Be Differentiated from Other Direct Thrombin Inhibitors: Experimental and Clinical Observations

  • 103
    Lopez, Mercedes; Nowak, Götz:

    Influence of Renal and Hepatic Failure on the Pharmacokinetics of Argatroban: An Experimental Study in Rats

  • 108
    Adiguzel, Cafer; Iqbal, Omer; Cunanan, Josephine; Jeske, Walter; Hoppensteadt, Debra; Walenga, Jeanine M.; Fareed, Jawed:

    Potency Adjusted Generic Versions of Argatroban Can Be Differentiated from Branded Argatroban in Thrombin Generation and Platelet Activation Assays

  • 119
    Fareed, Jawed; Walenga, Jeanine M.; Jeske, Walter P.; Hoppensteadt, Debra; Prechel, Margaret; Iqbal, Omer; Adiguzel, Cafer; Clark, Melanie; Litinas, Evangelos; Cunanan, Josephine; Linhardt, Robert; Harenberg, Job:

    Biological Profile of the Hyper/Oversulfated Chondroitin Sulfate Contaminant Isolated from Recalled Heparin

  • 128
    Fareed, Jawed; Walenga, Jeanine M.; Hoppensteadt, Debra A.; Bick, Rodger L.; Messmore, Harry L.:

    Dr. Eberhard F. Mammen Remembered: A Great Clinician-Scientist, Mentor, and Friend