CC BY-NC-ND 4.0 · Indian J Plast Surg 2014; 47(03): 432-435
DOI: 10.4103/0970-0358.146642
Case Report
Association of Plastic Surgeons of India

Closure of chronic non healing ankle ulcer with low level laser therapy in a patient presenting with thalassemia intermedia: Case report

Snehil Dixit
Department of Rehabilitation Sciences, College of Applied Medical Sciences, King Khalid University, Manipal, Karnataka, India
,
Parul Raj Agrawal
1   Department of Physiotherapy, School of Allied Health Sciences, Manipal, Karnataka, India
,
Dinesh Kumari Sharma
2   Department of Prosthodontics, Manipal College of Dental Sciences, Manipal, Karnataka, India
,
Ravindra Pratap Singh
3   Department of Community Medicine, Manipal University, Manipal, Karnataka, India
› Author Affiliations
Further Information

Address for correspondence

Dr. Snehil Dixit, Assistant Professor
Department of Rehabilitation Sciences, College of Applied Medical Sciences, King Khalid University
Saudi Arabia   

Publication History

Publication Date:
26 August 2019 (online)

 

ABSTRACT

In this single case study, the possible effect of low-level laser therapy (LLLT) was explored in the form of light emitting diodes on a chronic non-healing wound of 6 months duration in an 18-year-old male patient suffering from thalassemia intermedia. After irradiation, with LLLT dosage of 17.3 J/cm 2 for 8 min for 2 weeks duration followed by proliferative dosage of 8.65-4.33 J/cm 2 for 4 min from 3 rd week to 6 th week for 2 min along with antibiotics vancomycin (15 mg/kg) and a combination of amoxicillin and clavulanic acid (1 g). Proliferation of healthy granulation tissue was observed with decrease in score of pressure ulcer scale with complete re-epithelialization eventually LLLT irradiation could be a novel method of treatment for chronic non-healing wound in a thalassemia intermedia patient and an useful adjunct to standard care of treatment of pressure ulcers. It is postulated that LED irradiation augments wound healing with an early closure and no recurrence at the irradiated site even after follow up of 6 months.


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Conflict of Interest

None declared.

  • REFERENCES

  • 1 Henry M, Thompson J. Wound healing and management. Clinical Surgery 2 nd ed. London: Elsevier Saunders Limited; 2002: p. 105-13
  • 2 Gimmon Z, Wexler MR, Rachmilewitz EA. Juvenile leg ulceration in beta-thalassemia major and intermedia. Plast Reconstr Surg 1982; 69: 320-5
  • 3 Vagaskar SR, Fernandez RJ, Mistry FP. Leg ulcer in a case of thalassemia minor (a case report). J Postgrad Med 1989; 35: 120-1
  • 4 Dixit S, Maiya A, Umakanth S, Borkar S. Photobiomodulation of surgical wound dehiscence in a diabetic individual by low-level laser therapy following median sternotomy. Indian J Palliat Care 2013; 19: 71-5
  • 5 Dixit S, Maiya AG, Umakanth S, Shastry BA. Closure of non-healing chronic ulcer in Klippel-Trenaunay syndrome using low-level laser therapy. BMJ Case Rep 2012; 10: 1-4
  • 6 Taher AT, Musallam KM, Karimi M, El-Beshlawy A, Belhoul K, Daar S. et al. Overview on practices in thalassemia intermedia management aiming for lowering complication rates across a region of endemicity: The OPTIMAL CARE study. Blood 2010; 115: 1886-92
  • 7 Gardner SE, Hillis SL, Frantz RA. A prospective study of the PUSH tool in diabetic foot ulcers. J Wound Ostomy Continence Nurs 2011; 38: 385-93
  • 8 Sobanko JF, Alster TS. Efficacy of low-level laser therapy for chronic cutaneous ulceration in humans: A review and discussion. Dermatol Surg 2008; 34: 991-1000
  • 9 Whelan HT, Buchmann EV, Dhokalia A, Kane MP, Whelan NT, Wong-Riley MT. et al. Effect of NASA light-emitting diode irradiation on molecular changes for wound healing in diabetic mice. J Clin Laser Med Surg 2003; 21: 67-74

Address for correspondence

Dr. Snehil Dixit, Assistant Professor
Department of Rehabilitation Sciences, College of Applied Medical Sciences, King Khalid University
Saudi Arabia   

  • REFERENCES

  • 1 Henry M, Thompson J. Wound healing and management. Clinical Surgery 2 nd ed. London: Elsevier Saunders Limited; 2002: p. 105-13
  • 2 Gimmon Z, Wexler MR, Rachmilewitz EA. Juvenile leg ulceration in beta-thalassemia major and intermedia. Plast Reconstr Surg 1982; 69: 320-5
  • 3 Vagaskar SR, Fernandez RJ, Mistry FP. Leg ulcer in a case of thalassemia minor (a case report). J Postgrad Med 1989; 35: 120-1
  • 4 Dixit S, Maiya A, Umakanth S, Borkar S. Photobiomodulation of surgical wound dehiscence in a diabetic individual by low-level laser therapy following median sternotomy. Indian J Palliat Care 2013; 19: 71-5
  • 5 Dixit S, Maiya AG, Umakanth S, Shastry BA. Closure of non-healing chronic ulcer in Klippel-Trenaunay syndrome using low-level laser therapy. BMJ Case Rep 2012; 10: 1-4
  • 6 Taher AT, Musallam KM, Karimi M, El-Beshlawy A, Belhoul K, Daar S. et al. Overview on practices in thalassemia intermedia management aiming for lowering complication rates across a region of endemicity: The OPTIMAL CARE study. Blood 2010; 115: 1886-92
  • 7 Gardner SE, Hillis SL, Frantz RA. A prospective study of the PUSH tool in diabetic foot ulcers. J Wound Ostomy Continence Nurs 2011; 38: 385-93
  • 8 Sobanko JF, Alster TS. Efficacy of low-level laser therapy for chronic cutaneous ulceration in humans: A review and discussion. Dermatol Surg 2008; 34: 991-1000
  • 9 Whelan HT, Buchmann EV, Dhokalia A, Kane MP, Whelan NT, Wong-Riley MT. et al. Effect of NASA light-emitting diode irradiation on molecular changes for wound healing in diabetic mice. J Clin Laser Med Surg 2003; 21: 67-74