CC BY-NC-ND 4.0 · Indian J Plast Surg 2014; 47(02): 185-190
DOI: 10.4103/0970-0358.138939
Review Article
Association of Plastic Surgeons of India

Recent advances in head and neck cancer reconstruction

Prabha Yadav
1   Department of Surgery, Tata Memorial Hospital, Dr. E. Borges Marg, Parel, Mumbai, Maharashtra, India
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Address for correspondence:

Dr. Prabha Yadav
Department of Surgery, Tata Memorial Hospital
Dr. E. Borges Marg, Parel, Mumbai - 400 012, Maharashtra
India   

Publikationsverlauf

Publikationsdatum:
26. August 2019 (online)

 

ABSTRACT

Treatment of cancer is race against time! Following radical excision, breathing, speech, mastication and swallowing are hampered. Face is invariably involved. Beside functional normalcy, excellent cosmetic restoration is necessary for patient’s life quality. Primary wound healing, quick resumption of adequate oral intake, prompt initiation of chemo-radiotherapy has direct bearing on cure. Primary reconstruction with pedicle or free flap is the choice of treatment in most protocols. Composite defects are requiring bone, muscle and skin restrict choice of donor site and may have shortfalls in aesthetic and functional requirements. To improve further newer, and newer modalities are being developed and used to give best aesthetic and functions. Navigation, use of three-dimensional imaging, stereo lithic model and custom made implant for reconstruction are recommended as they promise improvement in aesthetics. Robotic surgeries allow access for resection of tumours and reconstruction with free flap in deep oropharynx obviating need of doing mandibulotomy. Researchers in stem cell and tissue engineering are looking forward to regenerating tissues and avoid the need of autologous tissue flaps. Desired tissue combination across counter may be available in the future. Excellent immunosuppressant drugs have made it possible to reconstruct composite facial anatomical units with allotransplant in a single surgery, along sensory and motor recovery! Mythological heterogenic head transplant like clone Ganesha, will be a reality in the near future!!


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Conflicts of interest

None declared.

  • REFERENCES

  • 1 Hurvitz KA, Kobayashi M, Evans GR. Current options in head and neck reconstruction. Plast Reconstr Surg 2006; 118: 122e-33
  • 2 Narain AK. Garain: The Idea and the Icon Brown, Robert (1991); Ganesh-Studies of an Asian God. ISBN: 0-7914-0657-1
  • 3 Understading Ganpathi: Insights into the dynamics of a cult. ISBN: 8173041954
  • 4 Grabb′s Encyclopedia of Flaps. Berish Strauch; Luis Vasconez: 2009. ISBN: 7181774926
  • 5 Janis JE, Kwon RK, Attinger CE. The new reconstructive ladder: Modifications to the traditional model. Plast Reconstr Surg 2011; 127 (Suppl. 01) supp 205S-12S
  • 6 Gill PS, Bidros RS, Boutros S. Reconstruction of oncological defects of the eyelid, lip and ear. Indian J Plast Surg 2007; 40 Supp S13-21
  • 7 Yadav P. Reconstruction surgery in oral cancers. Indian J Plast Surg 2007; 40 Suppl: S22-37
  • 8 Kuriakose MA, Loree TR, Spies A, Meyers S, Hicks Jr WL. Sensate radial forearm free flaps in tongue reconstruction. Arch Otolaryngol Head Neck Surg 2001; 127: 1463-6
  • 9 Yoleri L, Mavioglu H. Total tongue reconstruction with free functional gracilis muscle transplantation: A technical note and review of the literature. Ann Plast Surg 2000; 45: 181-6
  • 10 Iyer S, Thankappan K. Maxillary reconstruction: Current concepts and controversies. Indian J Plast Surg 2014; 47: 8-19
  • 11 Brown JS, Rogers SN, McNally DN, Boyle M. A modified classification for the maxillectomy defect. Head Neck 2000; 22: 17-26
  • 12 Dediol E, Uglešic V, Zubcic V, Kneževic P. Brown class III maxillectomy defects reconstruction with prefabricated titanium mesh and soft tissue free flap. Ann Plast Surg 2013; 71: 63-7
  • 13 Ahmed MM, Piper JM, Hansen NA, Sutton AJ, Schmalbach CE. Novel magnet-retained prosthetic system for facial reconstruction. JAMA Facial Plast Surg 2014; 16: 55-7
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  • 16 Yadav PS, Shankhdhar VK, Dushyant J, Seetharaman SS, Rajendra G. Two in one: Double free flap from a single free fibula osteocutaneous unit. Indian J Plast Surg 2012; 45: 459-65
  • 17 Wei FC, Demirkan F, Chen HC, Chen IH. Double free flaps in reconstruction of extensive composite mandibular defects in head and neck cancer. Plast Reconstr Surg 1999; 103: 39-47
  • 18 Wei FC, Yazar S, Lin CH, Cheng MH, Tsao CK, Chiang YC. Double free flaps in head and neck reconstruction. Clin Plast Surg 2005; 32: 303-8 v
  • 19 Moghadam HG, Urist MR, Sandor GK, Clokie CM. Successful mandibular reconstruction using a BMP bioimplant. J Craniofac Surg 2001; 12: 119-27
  • 20 Patel D, Kuriokose MA, Iyer A. Reconstruction of laryngopharynx. Indian J Plast Surg 2007; 40 Suppl: s44-51
  • 21 Collyer J. Stereotactic navigation in oral and maxillofacial surgery. Br J Oral Maxillofac Surg 2010; 48: 79-83
  • 22 Yamamoto T, Yamamoto N, Numahata T, Yokoyama A, Tashiro K, Yoshimatsu H. et al. Navigation lymphatic supermicrosurgery for the treatment of cancer-related peripheral lymphedema. Vasc Endovascular Surg 2014; 48: 139-43
  • 23 Evans BT, Webb AA. Post-traumatic orbital reconstruction: Anatomical landmarks and the concept of the deep orbit. Br J Oral Maxillofac Surg 2007; 45: 183-9
  • 24 Chang YM, Santamaria E, Wei FC, Chen HC, Chan CP, Shen YF. et al. Primary insertion of osseointegrated dental implants into fibula osteoseptocutaneous free flap for mandible reconstruction. Plast Reconstr Surg 1998; 102: 680-8
  • 25 Hanasono MM, Goel N, DeMonte F. Calvarial reconstruction with polyetheretherketone implants. Ann Plast Surg 2009; 62: 653-5
  • 26 Morris L, Sokoya M, Cunningham L, Gal TJ. Utility of stereolithographic models in osteocutaneous free flap reconstruction of the head and neck. Craniomaxillofac Trauma Reconstr 2013; 6: 87-92
  • 27 Selber JC. Transoral robotic reconstruction of oropharyngeal defects: A case series. Plast Reconstr Surg 2010; 126: 1978-87
  • 28 Langer R, Vacanti JP. Tissue engineering. Science 1993; 260: 920-6
  • 29 Shieh SJ, Terada S, Vacanti JP. Tissue engineering auricular reconstruction: In vitro and in vivo studies. Biomaterials 2004; 25: 1545-57
  • 30 Kojima K, Bonassar LJ, Roy AK, Mizuno H, Cortiella J, Vacanti CA. A composite tissue-engineered trachea using sheep nasal chondrocyte and epithelial cells. FASEB J 2003; 17: 823-8
  • 31 Kusumoto K, Beshha K, Fujimara K, Akioka J, Ogawa Y, Jizuka T. Prefabricated bone graft including bone induced by recombinant bone morphogenic protein-2: An experimental study of ectopic osteoinduction in rat latissmus dorsi muscle flap. Br J Plast Surg 1998; 51: 275-80
  • 32 Warnke PH, Springer IN, Wiltfang J, Acil Y, Eufinger H, Wehmöller M. et al. Growth and transplantation of a custom vascularised bone graft in a man. Lancet 2004; 364: 766-70
  • 33 Devauchelle B, Badet L, Lengelé B, Morelon E, Testelin S, Michallet M. et al. First human face allograft: Early report. Lancet 2006; 368: 203-9
  • 34 Gini Graham Scott: The very next new thing - Commentaries on latest development that will change your life. ISBN: 978-0-313-39411-9

Address for correspondence:

Dr. Prabha Yadav
Department of Surgery, Tata Memorial Hospital
Dr. E. Borges Marg, Parel, Mumbai - 400 012, Maharashtra
India   

  • REFERENCES

  • 1 Hurvitz KA, Kobayashi M, Evans GR. Current options in head and neck reconstruction. Plast Reconstr Surg 2006; 118: 122e-33
  • 2 Narain AK. Garain: The Idea and the Icon Brown, Robert (1991); Ganesh-Studies of an Asian God. ISBN: 0-7914-0657-1
  • 3 Understading Ganpathi: Insights into the dynamics of a cult. ISBN: 8173041954
  • 4 Grabb′s Encyclopedia of Flaps. Berish Strauch; Luis Vasconez: 2009. ISBN: 7181774926
  • 5 Janis JE, Kwon RK, Attinger CE. The new reconstructive ladder: Modifications to the traditional model. Plast Reconstr Surg 2011; 127 (Suppl. 01) supp 205S-12S
  • 6 Gill PS, Bidros RS, Boutros S. Reconstruction of oncological defects of the eyelid, lip and ear. Indian J Plast Surg 2007; 40 Supp S13-21
  • 7 Yadav P. Reconstruction surgery in oral cancers. Indian J Plast Surg 2007; 40 Suppl: S22-37
  • 8 Kuriakose MA, Loree TR, Spies A, Meyers S, Hicks Jr WL. Sensate radial forearm free flaps in tongue reconstruction. Arch Otolaryngol Head Neck Surg 2001; 127: 1463-6
  • 9 Yoleri L, Mavioglu H. Total tongue reconstruction with free functional gracilis muscle transplantation: A technical note and review of the literature. Ann Plast Surg 2000; 45: 181-6
  • 10 Iyer S, Thankappan K. Maxillary reconstruction: Current concepts and controversies. Indian J Plast Surg 2014; 47: 8-19
  • 11 Brown JS, Rogers SN, McNally DN, Boyle M. A modified classification for the maxillectomy defect. Head Neck 2000; 22: 17-26
  • 12 Dediol E, Uglešic V, Zubcic V, Kneževic P. Brown class III maxillectomy defects reconstruction with prefabricated titanium mesh and soft tissue free flap. Ann Plast Surg 2013; 71: 63-7
  • 13 Ahmed MM, Piper JM, Hansen NA, Sutton AJ, Schmalbach CE. Novel magnet-retained prosthetic system for facial reconstruction. JAMA Facial Plast Surg 2014; 16: 55-7
  • 14 Delacure M. Reconstruction of the mandible. Indian J Plast Surg 2007; 40 Suppl s28-34
  • 15 Jones NF, Vögelin E, Markowitz BL, Watson JP. Reconstruction of composite through-and-through mandibular defects with a double-skin paddle fibular osteocutaneous flap. Plast Reconstr Surg 2003; 112: 758-65
  • 16 Yadav PS, Shankhdhar VK, Dushyant J, Seetharaman SS, Rajendra G. Two in one: Double free flap from a single free fibula osteocutaneous unit. Indian J Plast Surg 2012; 45: 459-65
  • 17 Wei FC, Demirkan F, Chen HC, Chen IH. Double free flaps in reconstruction of extensive composite mandibular defects in head and neck cancer. Plast Reconstr Surg 1999; 103: 39-47
  • 18 Wei FC, Yazar S, Lin CH, Cheng MH, Tsao CK, Chiang YC. Double free flaps in head and neck reconstruction. Clin Plast Surg 2005; 32: 303-8 v
  • 19 Moghadam HG, Urist MR, Sandor GK, Clokie CM. Successful mandibular reconstruction using a BMP bioimplant. J Craniofac Surg 2001; 12: 119-27
  • 20 Patel D, Kuriokose MA, Iyer A. Reconstruction of laryngopharynx. Indian J Plast Surg 2007; 40 Suppl: s44-51
  • 21 Collyer J. Stereotactic navigation in oral and maxillofacial surgery. Br J Oral Maxillofac Surg 2010; 48: 79-83
  • 22 Yamamoto T, Yamamoto N, Numahata T, Yokoyama A, Tashiro K, Yoshimatsu H. et al. Navigation lymphatic supermicrosurgery for the treatment of cancer-related peripheral lymphedema. Vasc Endovascular Surg 2014; 48: 139-43
  • 23 Evans BT, Webb AA. Post-traumatic orbital reconstruction: Anatomical landmarks and the concept of the deep orbit. Br J Oral Maxillofac Surg 2007; 45: 183-9
  • 24 Chang YM, Santamaria E, Wei FC, Chen HC, Chan CP, Shen YF. et al. Primary insertion of osseointegrated dental implants into fibula osteoseptocutaneous free flap for mandible reconstruction. Plast Reconstr Surg 1998; 102: 680-8
  • 25 Hanasono MM, Goel N, DeMonte F. Calvarial reconstruction with polyetheretherketone implants. Ann Plast Surg 2009; 62: 653-5
  • 26 Morris L, Sokoya M, Cunningham L, Gal TJ. Utility of stereolithographic models in osteocutaneous free flap reconstruction of the head and neck. Craniomaxillofac Trauma Reconstr 2013; 6: 87-92
  • 27 Selber JC. Transoral robotic reconstruction of oropharyngeal defects: A case series. Plast Reconstr Surg 2010; 126: 1978-87
  • 28 Langer R, Vacanti JP. Tissue engineering. Science 1993; 260: 920-6
  • 29 Shieh SJ, Terada S, Vacanti JP. Tissue engineering auricular reconstruction: In vitro and in vivo studies. Biomaterials 2004; 25: 1545-57
  • 30 Kojima K, Bonassar LJ, Roy AK, Mizuno H, Cortiella J, Vacanti CA. A composite tissue-engineered trachea using sheep nasal chondrocyte and epithelial cells. FASEB J 2003; 17: 823-8
  • 31 Kusumoto K, Beshha K, Fujimara K, Akioka J, Ogawa Y, Jizuka T. Prefabricated bone graft including bone induced by recombinant bone morphogenic protein-2: An experimental study of ectopic osteoinduction in rat latissmus dorsi muscle flap. Br J Plast Surg 1998; 51: 275-80
  • 32 Warnke PH, Springer IN, Wiltfang J, Acil Y, Eufinger H, Wehmöller M. et al. Growth and transplantation of a custom vascularised bone graft in a man. Lancet 2004; 364: 766-70
  • 33 Devauchelle B, Badet L, Lengelé B, Morelon E, Testelin S, Michallet M. et al. First human face allograft: Early report. Lancet 2006; 368: 203-9
  • 34 Gini Graham Scott: The very next new thing - Commentaries on latest development that will change your life. ISBN: 978-0-313-39411-9