LDL-receptor-deficient mice lacking microRNA-143/145 have less atherosclerosis

Insight on: Sala et al. Thromb Haemost 2014; 112: 796-802.

• References

• 1 Boettger T, Beetz N, Kostin S. et al. Acquisition of the contractile phenotype by murine arterial smooth muscle cells depends on the Mir143/145 gene cluster. J Clin Invest 2009; 119: 2634-2647.
• 2 Sala F, Aranda JF, Rotllan N. et al. MiR-143/145 deficiency protects against progression of atherosclerosis in Ldlr-/-mice. Thromb Haemost 2014; 112: 796-802.
• 3 Hergenreider E, Heydt S, Tréguer K. et al. Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs. Nat Cell Biol 2012; 14: 249-256.