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Thromb Haemost 2008; 100(01): 158-160
DOI: 10.1160/TH08-04-0260
Letters to the Editor
Schattauer GmbH

Factor XI protein in human pancreas and kidney

Qiufang Cheng
1   Departments of Pathology, Vanderbilt University, Nashville, Tennessee, USA
,
Jeanelle Kantz
2   Molecular Biology and Biophysics, Vanderbilt University, Nashville, Tennessee, USA
,
Greg Poffenberger
3   Medicine, Vanderbilt University, Nashville, Tennessee, USA
,
Alvin C. Powers
1   Departments of Pathology, Vanderbilt University, Nashville, Tennessee, USA
3   Medicine, Vanderbilt University, Nashville, Tennessee, USA
4   VA Tennessee Valley Healthcare System, Nashville, Tennessee, USA
,
David Gailani
1   Departments of Pathology, Vanderbilt University, Nashville, Tennessee, USA
3   Medicine, Vanderbilt University, Nashville, Tennessee, USA
› Author AffiliationsFinancial support: This work was supported by grants from the National Heart, Lung, and Blood Institute (HL58837); the National Institute of Diabetes and Digestive and Kidney Diseases (DK69603, DK 66636); the American Heart Association; the Veterans Administration; the Juvenile Diabetes Research Foundation International; and the Vanderbilt Diabetes Research and Training Center (DK20593).
Further Information

Publication History

Received 25 April 2008

Accepted 12 May 2008

Publication Date:
22 November 2017 (online)

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  • References

  • 1 Seligsohn U. Factor XI in haemostasis and thrombosis: Past, present and future. Thromb Haemost 2007; 98: 84-89.
    Article in Thieme ConnectPubMedGoogle Scholar
  • 2 Tarumi T, Kravtsov D, Zhao M. et al. Cloning and characterization of the human factor XI gene promoter: transcription factor hepatocyte nuclear factor 4α (HNF-4α) is required for hepatocyte-specific expression of factor XI. J Biol Chem 2002; 277: 18510-18516.
    CrossrefPubMedGoogle Scholar
  • 3 Walker IR, Milner RA, Johnston MA. et al. Factors XI and XII are low in subjects with liver disease. Dig Dis Sci 1983; 28: 967-970.
    CrossrefPubMedGoogle Scholar
  • 4 Gailani D, Sun M-F, Sun Y. A comparison of murine and human factor XI. Blood 1997; 90: 1055-1064.
    PubMedGoogle Scholar
  • 5 Fujikawa K, Chung D, Hendrickson L. et al. Amino acid sequence of human factor XI, a blood coagulation factor with four tandem repeats that are highly homologous with plasma prekallikrein. Biochemistry 1986; 25: 2417-2424.
    CrossrefPubMedGoogle Scholar
  • 6 Sun Y, Gailani D. Identification of a factor IX binding site on the third apple domain of activated factor XI. J Biol Chem 1996; 271: 29023-29028.
    CrossrefPubMedGoogle Scholar
  • 7 Ozmen L, Ekdahl K, Elgue G. et al. Inhibition of thrombin abrogates the instant blood-mediated inflammatory reaction triggered by isolated human islets: possible application of the thrombin inhibitor melagatran in clinical islet transplantation. Diabetes 2002; 51: 1779-1784.
    CrossrefPubMedGoogle Scholar
  • 8 Froberg M, Leone J, Jessurun J. et al. Fatal disseminated intravascular coagulation after autologous islet transplantation. Hum Pathol 1997; 28: 1295-1298.
    CrossrefPubMedGoogle Scholar
  • 9 Shapiro AM, Lakey JR, Rajotte RV. et al. Portal vein thrombosis after transplantation of partially purified pancreatic islets in a combined human liver/islet allograft. Transplantation 1995; 59: 1060-1063.
    CrossrefPubMedGoogle Scholar
  • 10 Meijers JC, Tekelenburg WL, Bouma BN. et al. High levels of coagulation factor XI as a risk factor for venous thrombosis. N Engl J Med 2000; 342: 696-701.
    CrossrefPubMedGoogle Scholar
  • 11 Odom D, Zizlsperger N, Gordon D. et al. Control of pancreas and liver gene expression by HNF transcription factors. Science 2004; 303: 1378-1381.
    CrossrefPubMedGoogle Scholar
  • 12 Miura A, Yamagata K, Kakei M. et al. Hepatoctye nuclear factor-4α is essential for glucose-stimulated secretion by pancreatic beta cells. J Biol Chem 2006; 281: 5246-5257.
    CrossrefPubMedGoogle Scholar
  • 13 Sladek F. Hepatocyte Nuclear Factor 4. Liver Gene Expression. Landis: Austin Texas; 1994: 207-230.
    Google Scholar
  • 14 Fink E, Bhoola KD, Snyman C. et al. Cellular expression of plasma prekallikrein in human tissues. Biol Chem 2007; 388: 957-963.
    PubMedGoogle Scholar