Download PDF
Thromb Haemost 2008; 99(05): 966-968
DOI: 10.1160/TH08-03-0152
Letters to the Editor
Schattauer GmbH

Request for further standardization issues for future studies in paediatric haemophilia patients – Rebuttal to “Including the life-time cumulative number of joint bleeds in the definition of primary prophylaxis”

Susan Halimeh
1   Dept. of Pediatric Hematology and Oncology, University Hospital Münster, Germany
,
Anne Krümpel
1   Dept. of Pediatric Hematology and Oncology, University Hospital Münster, Germany
,
Rosemarie Schobess
2   Dept. of Pediatrics, University Hospital Halle, Germany
,
Karin Kurnik
3   Dept. of Pediatrics, University Hospital Munich, Germany
,
Frauke Friedrichs
4   Leibniz-Institute for Arteriosclerosis Research, University of Münster, Germany
,
Christoph Bidlingmaier
3   Dept. of Pediatrics, University Hospital Munich, Germany
,
Ulrike Nowak-Göttl
1   Dept. of Pediatric Hematology and Oncology, University Hospital Münster, Germany
› Author AffiliationsFinancial support: This study was supported by unrestricted grants from Bayer Vital GmbH, CSL Behring GmbH (Hattersheim, Germany) and Octapharma GmbH (Langenfeld, Germany).
Further Information

Publication History

Received 10 March 2008

Accepted after minor revision 01 April 2008

Publication Date:
30 November 2017 (online)

    Permissions and Reprints

 

 

  • References

  • 1 den Uijl IEM, Fischer K. Including the life-time cumulative number of joint bleeds in the definition of primary prophylaxis. Thromb Haemost 2008; 99: 965.
    Article in Thieme ConnectPubMedGoogle Scholar
  • 2 Schobess R, Kurnik K, Friedrichs F. et al. Effects of primary and secondary prophylaxis on the clinical expression of joint damage in children with severe hemophilia A – Results of a multicenter non-concurrent cohort study. Thromb Haemost 2008; 99: 71-76.
    Article in Thieme ConnectPubMedGoogle Scholar
  • 3 Berntorp E, Astermark J, Björkman S. et al. Consensus perspectives on prophylactic therapy for haemophilia: summary statement. Haemophilia 2003; 9: 1-4.
    PubMedGoogle Scholar
  • 4 Ota S, Mclimont M, Carcao MD. et al. Definitions for haemophilia prophylaxis and its outcomes: The Canadian Consensus Study. Haemophilia 2007; 13: 12-20.
    CrossrefPubMedGoogle Scholar
  • 5 Pettersson H, Nilsson IM, Hedner U. et al. Radiologic evaluation of prophylaxis in severe haemophilia. Acta Paed Scand 1981; 70: 565-570.
    CrossrefPubMedGoogle Scholar
  • 6 Nuss R, Kilcoyne RF, Geraghty S. et al. MRI findings in haemophilic joints treated with radiosynoviorthesis with development of an MRI scale of joint damage. Haemophilia 2000; 6: 162-169.
    CrossrefPubMedGoogle Scholar
  • 7 Fischer K, van der Bom JG, Mauser-Bunschoten EP. et al. The effects of postponing prophylactic treatment on long-term outcome in patients with severe hemophilia. Blood 2002; 99: 2337-2341.
    CrossrefPubMedGoogle Scholar
  • 8 Kreuz W, Escuriola Ettingshausen C, Funk M. et al. Prevention of joint damage in hemophiliac children with early prophylaxis. Orthopäde 1999; 28: 341-346.
    PubMedGoogle Scholar
  • 9 Manco-Johnson MJ, Abshire TC, Shapiro AD. et al. Prophylaxis versus episodic treatment to prevent joint disease in boys with severe hemophilia. N Engl J Med 2007; 357: 535-544.
    CrossrefPubMedGoogle Scholar