Protein C deficiency screening using a thrombin-generation assay

Thromb Haemost 2007; 97(01): 165-166
DOI: 10.1160/TH06-09-0530

Letters to the Editor

Schattauer GmbH

Nathalie Hézard

¹Laboratoire d’Hématologie, CHU Robert Debré, Reims, France

,

Lobna Bouaziz-Borgi

¹Laboratoire d’Hématologie, CHU Robert Debré, Reims, France

²Unité de Recherche des Maladies Hématologiques et Auto-Immunes, Faculté de Pharmacie, Monastir, Tunisia

,

Marie-Geneviève Remy

¹Laboratoire d’Hématologie, CHU Robert Debré, Reims, France

,

Bernadette Florent

¹Laboratoire d’Hématologie, CHU Robert Debré, Reims, France

,

Philippe Nguyen

¹Laboratoire d’Hématologie, CHU Robert Debré, Reims, France

References
1 Hézard N, Bouaziz-Borgi L, Remy MG. et al Utility of thrombin-generation assay in the screening of Factor V G1691A (Leiden) and prothrombin G20210A mutations and PS deficiency. Clin Chem 2006; 52: 665-70.
2 Regnault V, Hemker HC, Wahl D. et al Phenotyping the haemostatic system by thrombinography-potential for the estimation of thrombotic risk. Thromb Res 2004; 114: 539-45.
3 Martinoli JL, Stocker K. Fast functional protein C assay using Protac, a novel protein C activator. Thromb Res 1986; 43: 253-64.
4 Cvirn G, Gallistl S, Muntean W. Effects of antithrombin and protein C on thrombin generation in newborn and adult plasma. Thromb Res 1999; 93: 183-90.
5 Hemker HC, Giesen P, Al Dieri R. et al The Calibrated Automated Thrombogram (CAT): a universal routine test for hyper-and hypocoaguability. Pathophysiol Haemost Thromb 2002; 32: 249-53.
6 Regnault V, Beguin S, Lecompte T. Calibrated automated thrombin generation in frozen-thawed plateletrich plasma to detect hypercoagulability. Pathophysiol Haemost Thromb 2003; 33: 23-9.