Tissue engineering of heart valves - hype or hope?

Thromb Haemost 2005; 94(03): 469-470
DOI: 10.1160/TH05-07-0528

Editorial Focus

Schattauer GmbH

Authors

Ulrich A. Stock

¹Dept. of Medical Physics and Biophysics, Humboldt University, University Hospital Charité, Berlin, Germany

²Dept. Cardiac Surgery, Heart Center Brandenburg, Bernau / Berlin, Germany

References
1 Kasimir MT, Weigel G, Sharma J. et al. The decellularized porcine heart valve matrix in tissue engineering: Platelet adhesion and activation.. Thromb Haemost 2005; 94: 562-7.
2 Bechtel JF, Muller-Steinhardt M, Schmidtke C. et al. Evaluation of the decellularized pulmonary valve homograft (SynerGraft).. J Heart Valve Dis 2003; 12: 734-9.
3 Simon P, Kasimir MT, Seebacher G. et al. Early failure of the tissue engineered porcine heart valve Syner-Graft in pediatric patients.. Eur J Cardiothorac Surg 2003; 23: 1002-6.
4 Rieder E, Kasimir MT, Seebacher G. et al. Tissue engineering of heart valve conduit of porcine or human origin differ importantly in chemotactic activity for monocytic cells.. Circulation 2005; 111: 2792-7.
5 Schenke-Layland K, Riemann I, Opitz F. et al. Comparative study of cellular and extracellular matrix composition of native and tissue engineered heart valves.. Matrix Biol 2004; 23: 113-25.
6 Schenke-Layland K, Opitz F, Gross M. et al. Complete dynamic repopulation of decellularized heart valves by application of defined physical signals – an in vitro study.. Cardiovasc Res 2003; 60: 497-509.