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DOI: 10.1055/s-2007-966612
© Georg Thieme Verlag KG Stuttgart · New York
Multiple stenting in a patient with a high-grade malignant hilar biliary stricture: endoscopic four-branched partial stent-in-stent deployment of metallic stents
H. Kawamoto, MD
Department of Gastroenterology and Hepatology
Okayama University Graduate School of Medicine and Dentistry
2-5-1 Shikata-cho
Okayama City 700-8558
Japan
Fax: +81-86-225-5991
Email: h-kawamo@md.okayama-u.ac.jp
Publication History
Publication Date:
05 July 2007 (online)
Palliative therapy, such as biliary stenting, is often required before chemotherapy in patients with cholangiocellular carcinoma, who often have a hilar biliary stricture. In addition, chemotherapy itself puts patients at a higher risk of cholangitis. Drainage of both hepatic lobes is more advantageous than drainage of a single lobe alone, to avoid the development of cholangitis in the other lobe [1] [2], but the deployment of multiple stents in a hilar biliary stricture is technically demanding. We report here the endoscopic four-branched partial stent-in-stent deployment of metallic stents in a patient with a Bismuth type IV hilar biliary stricture.
A 64-year-old man was admitted to our hospital with a liver tumor, dilatation of the intrahepatic bile ducts, and abnormal liver function tests. He had no jaundice at the time of admission, but his serum alkaline phosphatase was raised at 947 IU/L. Endoscopic cholangiography showed that he had a Bismuth type IV stricture ([Fig. 1]). Furthermore, in the anterior segment of the liver the bile ducts were stenotic at the bifurcation of S5 and S8 due to tumor invasion. Because the patient had para-aortic lymph node metastasis, we judged that the tumor was unresectable and that he should receive chemotherapy. Before chemotherapy, we placed four JoStent SelfX stents (Abbott Vascular Devices, Redwood City, California, USA) - in the left lateral segment, in S5 and S8 of the right anterior segment, and in the right posterior segment - using the partial stent-in-stent procedure ([Fig. 2]). To facilitate placement, we first identified the target branches and inserted 0.025-inch guide wires into them as landmarks for the bifurcation ([Fig. 3]). The patient was discharged and began chemotherapy with gemcitabine as an outpatient. He lived for more than 1 year without jaundice. This case confirms that the JoStent SelfX is suitable for the management of high-grade malignant hilar biliary stricture [3].
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#References
- 1 Devière J, Motte S, Dumonceau J M. et al . Septicemia after endoscopic retrograde cholangiopancreatography. Endoscopy. 1990; 22 72-75
- 2 Dumas R, Demuth N, Buckley M. et al . Endoscopic bilateral metal stent placement for malignant hilar stenosis: identification of optimal technique. Gastrointest Endosc. 2000; 51 334-338
- 3 Kawamoto H, Ishida E, Ogawa T. et al . Multiple stenting in hilar bile duct carcinoma: three-branched partial stent-in-stent deployment with the JOSTENT SelfX. Endoscopy. 2004; 36 829-830
H. Kawamoto, MD
Department of Gastroenterology and Hepatology
Okayama University Graduate School of Medicine and Dentistry
2-5-1 Shikata-cho
Okayama City 700-8558
Japan
Fax: +81-86-225-5991
Email: h-kawamo@md.okayama-u.ac.jp
References
- 1 Devière J, Motte S, Dumonceau J M. et al . Septicemia after endoscopic retrograde cholangiopancreatography. Endoscopy. 1990; 22 72-75
- 2 Dumas R, Demuth N, Buckley M. et al . Endoscopic bilateral metal stent placement for malignant hilar stenosis: identification of optimal technique. Gastrointest Endosc. 2000; 51 334-338
- 3 Kawamoto H, Ishida E, Ogawa T. et al . Multiple stenting in hilar bile duct carcinoma: three-branched partial stent-in-stent deployment with the JOSTENT SelfX. Endoscopy. 2004; 36 829-830
H. Kawamoto, MD
Department of Gastroenterology and Hepatology
Okayama University Graduate School of Medicine and Dentistry
2-5-1 Shikata-cho
Okayama City 700-8558
Japan
Fax: +81-86-225-5991
Email: h-kawamo@md.okayama-u.ac.jp