ABSTRACT
Significant progress has been made in the molecular characterization of the hepatic
amino acid transport systems, processes that play a key role in hepatocellular functions
such as gluconeogenesis and glycogen formation, and the response of the hepatocyte
to injury. Several amino acid transporters have been cloned, and regulation of hepatic
amino acid transport under normal and pathophysiologic conditions can now be examined
in greater detail. Recent work on the hepatic amino acid transport systems is reviewed,
and the clinical implications of these findings, if known, are discussed.
KEY WORDS
alanine - glutamine - arginine
