We have categorized reperfusion injury into (1) warm ischemia/reperfusion injury and
(2) cold storage/reperfusion injury. Warm ischemia/reperfusion injury is relevant
to shock and hepatic surgery, whereas cold storage/reperfusion injury occurs when
the liver is procured and transported for transplantation. Different stages of reperfusion
injury; cells that mediate each stage; and cytokines involved are described. Understanding
the specific cells and cytokines involved in causing reperfusion injury and their
timing will encourage the development of therapeutic strategies aimed at preventing
and diminishing the consequences of reperfusion injury.
reperfusion injury - ischemia - hypoxia