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DOI: 10.1055/s-2006-951722
Free Radical-Scavenging δ-Lactones from Boletus calopus
Publication History
Received: July 15, 2006
Accepted: September 15, 2006
Publication Date:
07 November 2006 (online)
Abstract
The methanol extracts from the fruiting body of the mushroom Boletus calopus showed free radical-scavenging activity. Bioactivity-guided fractionation of the methanol extracts led to a new hydroxylated calopin named calopin B, along with the known δ-lactones calopin and cyclocalopin A. The structure of the new calopin analogue was elucidated by spectroscopic methods. All compounds showed potent free radical-scavenging activity against superoxide, DPPH, and ABTS radicals with IC50 values of 1.2 - 5.4 μg/mL.
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Dr. Won-Gon Kim
Functional Metabolomics Research Center
Korea Research Institute of Bioscience and Biotechnology
Daejeon 305-806
Korea
Phone: +82-42-860-4298
Fax: +82-42-860-4595
Email: wgkim@kribb.re.kr
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