SLN-Diagnostik bei Tumoren des Beckens

Zusammenfassung

Da sich die Tumoren des Beckens nicht zu einer einheitlichen Entität zusammenfassen lassen, soll in dieser Übersichtsarbeit auf die Sentinel-Lymph-Node(SLN)-Technik jeweils getrennt für das Penis-, Prostata-, Vulva-, Zervix- und Harnblasenkarzinom eingegangen werden.

Abstract

Since the different tumour entities of the pelvis have nothing in common, we will in this review discuss separately for each tumour the sentinel lymph node (SLN)-technique in penile, prostate, vulvar, cervical, and bladder cancer.

Schlüsselwörter

Schildwächterlymphknoten - SLN - Beckentumoren - Peniskarzinom - Prostatakarzinom - Vulvakarzinom - Zervixkarzinom - Harnblasenkarzinom

Key words

sentinel lymph node - SLN - tumours of the pelvis - penile cancer - prostate cancer - vulvar cancer - cervical cancer - bladder cancer

Literatur

• 1 Cabanas R M. An approach for the treatment of penile carcinoma.  Cancer. 1977;  39 456-466
• 2 Kroon B K, Horenblas S, Meinhardt W, der Poel H G van, Bex A, Tinteren H van, Valdes Olmos R A, Nieweg O E. Dynamic sentinel node biopsy in penile carcinoma: evaluation of 10 years experience.  Eur Urol. 2005;  47 601-606
• 3 Solsona E, Algaba F, Horenblas S, Pizzocaro G, Windahl T. EAU guidelines on penile cancer.  Eur Urol. 2004;  46 1-8
• 4 Wawroschek F, Vogt H, Bachter D, Weckermann D, Hamm M, Harzmann R. First experience with gamma probe guided sentinel lymph node surgery in penile cancer.  Urol Res. 2000;  28 246-249
• 5 Kroon B K, Horenblas S, Estourgie S H, Lont A P, Valdes Olmos R A, Nieweg O E. How to avoid false-negative dynamic sentinel node procedures in penile carcinoma.  J Urol. 2004;  171 2191-2194
• 6 Kroon B K, Valdes Olmos R, Nieweg O E, Horenblas S. Non-visualization of sentinel lymph nodes in penile carcinoma.  Eur J Nucl Med Mol Imaging. 2005;  32 1096-1099
• 7 Bader P, Burkhard F C, Markwalder R, Studer U E. Disease progression and survival of patients with positive lymph nodes after radical prostatectomy. Is there a chance of cure?.  J Urol. 2003;  169 849-854
• 8 Gardiner R A, Fitzpatrick J M, Constable A R, Crawage R W, O'Donoghue E P, Wickham J EA. Human prostatic lymphoscintigraphy: a preliminary report.  Br J Urol. 1979;  51 300 a
• 9 Suzuki T, Kurokawa K, Yamanaka H, Jimbo H. Lymphatic drainage of the prostate gland in canines.  Prostate. 1992;  21 279-286
• 10 Wawroschek F, Vogt H, Weckermann D, Wagner T, Harzmann R. Identifikation der Schildwächter-Lymphknoten des Prostatakarzinoms - Ergebnisse eines neuen Stagingverfahrens.  Der Nuklearmediziner. 1999;  22 283-291
• 11 Heidenreich P, Vogt H, Bachter D, Büchels H, Steinfeld D, Wawroschek F, Wengenmair H, Wagner T. Das Konzept des Wächterlymphknotens: Stand und klinische Bedeutung.  Dt Ärztebl. 2001;  98 A534-A548
• 12 Dorn R, Wengenmair H, Sciuk J, Vogt H, Wawroschek F. Szintigraphischer Nachweis ungewöhnlicher Lymphabstromgebiete der Prostata: Analyse der Szintigramme und des intraoperativen Situs von 998 Patienten.  Nuklearmedizin. 2004;  43 A88
• 13 Jeschke S, Nambirajan T, Leeb K, Ziegerhofer J, Sega W, Janetschek G. Detection of early lymph node metastases in prostate cancer by laparoscopic radioisotope guided sentinel lymph node dissection.  J Urol. 2005;  173 1943-1946
• 14 Wawroschek F, Vogt H, Weckermann D, Wagner T, Hamm M, Harzmann R. Radioisotope guided pelvic lymphe node dissection for prostate cancer.  J Urol. 2001;  166 1715-1719
• 15 Weckermann D, Wawroschek F, Harzmann R. Is there a need for pelvic lymph node dissection in low risk prostate cancer patients prior to definitive local therapy?.  Eur Urol. 2005;  47 45-50
• 16 Aus G, Abbou C C, Pacik D, Schmid H-P, Poppel H van, Wolff J M, Zattoni F. EAU guidelines on prostate cancer.  Eur Urol. 2001;  40 97-101
• 17 de Hullu J A, Doting E, Piers D A, Hollema H, Aalders J G, Koops H S, Boonstra H, der Zee A GJ van. Sentinel lymph node identification with technetium-99m-labeled nanocolloid in squamous cell cancer of the vulva.  J Nucl Med. 1998;  39 1381-1385
• 18 de Hullu J A, Hollema H, Piers D A, Verheijen R HM, Diest P J van, Mourits M JE, Aalders J G, der Zee A GJ van. Sentinel lymph node procedure is highly accurate in squamous cell carcinoma of the vulva.  J Clin Oncol. 2000;  18 2811-2816
• 19 Merisio C, Beretta R, Gualdi M, Pultrone D C, Anfuso S, Agnese G, Aprile C, Mereu L, Salamano S, Tateo S, Melpignano M. Radioguided sentinel lymph node detection in vulvar cancer.  Int J Gynecol Cancer. 2005;  15 493-497
• 20 Louis-Sylvestre C, Evangelista E, Leonard F, Itti E, Meignan M, Paniel B J. Sentinel node localization should be interpreted with caution in midline vulvar cancer.  Gynecol Oncol. 2005;  97 151-154
• 21 Selman T J, Luesley D M, Acheson N, Khan K S, Mann C H. A systematic review of the accuracy of diagnostic tests for inguinal lymph node status in vulvar cancer.  Gynecol Oncol. 2005;  99 206-214
• 22 Roca I, Caresia A P, Gil-Moreno A, Pifarre P, Aguade-Bruix S, Castell-Conesa J, Martinez-Palones J M, Xercavins J. Usefulness of sentinel lymph node detection in early stages of cervical cancer.  Eur J Nucl Med Mol Imaging. 2005;  32 1210-1216
• 23 Pijpers R, Buist M R, Lingen A van, Dijkstra J, Diest P J van, Teule G J, Kenemans P, Verheijen R H. The sentinel node in cervical cancer: scintigraphy and laparoscopic gamma probe-guided biopsy.  Eur J Nucl Med Mol Imaging. 2004;  31 1479-1486
• 24 Marchiole P, Buenerd A, Scoazec J Y, Dargent D, Mathevet P. Sentinel lymph node biopsy is not accurate in predicting lymph node status for patients with cervical carcinoma.  Cancer. 2004;  100 2154-2159
• 25 Levenback C, Coleman R L, Burke T W, Lin W M, Erdman W, Deavers M, Delpassand E S. Lymphatic mapping and sentinel node identification in patients with cervix cancer undergoing radical hysterectomy and pelvic lymphadenectomy.  J Clin Oncol. 2002;  20 688-693
• 26 Barranger E, Grahek D, Cortez A, Talbot J N, Uzan S, Darai E. Laparoscopic sentinel lymph node procedure using a combination of patent blue and radioisotope in women with cervical carcinoma.  Cancer. 2003;  97 2945-2947
• 27 Barranger E, Coutant C, Cortez A, Uzan S, Darai E. Sentinel node biopsy is reliable in early-stage cervical cancer but not in locally advanced disease.  Ann Oncol. 2005;  16 1237-1242
• 28 Sherif A, De La Torre M, Malmstrom P U, Thorn M. Lymphatic mapping and detection of sentinel nodes in patients with bladder cancer.  J Urol. 2001;  166 812-815
• 29 Liedberg F, Chebil G, Davidsson T, Malmstrom P U, Sherif A, Thorn M, De La Torre M, Mansson W. Bladder cancer and the sentinel node concept.  Aktuelle Urol. 2003;  34 115-118