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Geburtshilfe Frauenheilkd 2005; 65(12): 1182-1185
DOI: 10.1055/s-2005-872942
Fallbericht

Georg Thieme Verlag KG Stuttgart · New York

Fallopian Tube Carcinoma - a Rare Gynaecological Malignancy - Case Report and Review of Literature

Das Tubenkarzinom - ein seltenes gynäkologisches Malignom Fallbericht und LiteraturübersichtB. Krämer1 , T. Fehm1 , B. Schauf1 , E. Krämer1 , D. Wallwiener1 , G. Meyberg1 , E. F. Solomayer1
  • 1Department of Obstetrics and Gynecology, Women's University Hospital of the University of Tuebingen, Germany
Further Information

Publication History

Eingang Manuskript: 16.9.2005

Akzeptiert: 5.10.2005

Publication Date:
18 January 2006 (online)

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Zusammenfassung

Das Tubenkarzinom ist das seltenste gynäkologische Malignom und umfasst 0,1 - 1 % der Tumoren des weiblichen Genitaltrakts. Es wird selten präoperativ diagnostiziert, meist erfolgt eine Operation aus anderer Ursache. Fallbericht: 56-jährige postmenopausale Patientin mit primärem Tubenkarzinom im Stadium III, Begrenzung auf die rechte Tube - ein positiver retroperitonealer Lymphknoten. Nach Resektion wurde eine adjuvante Chemotherapie mit 6 Zyklen Carboplatin/Taxol empfohlen. Schlussfolgerung: Aufgrund der Seltenheit des Tubenkarzinoms sind randomisierte Studien zur Therapiefestlegung schwierig.

Abstract

Background: Primary fallopian tube carcinoma is the rarest of all gynaecological malignancies. It comprises only 0.1 - 1.0 % of all neoplasms of the female genital tract, although it is a common site of metastases. This carcinoma is rarely diagnosed preoperatively; most often patients undergo surgery for other reasons. Case: We report the case of a 56-year-old postmenopausal woman with primary fallopian tube carcinoma third stage confined to the right tube involving one positive retroperitoneal lymph node. Adjuvant chemotherapy with six cycles of Carboplatin/Taxol was advised after surgical resection. Conclusion: The rarity of the condition makes it difficult to perform randomised studies which could determine the treatment of choice. Our work adds further information to the relatively small body of literature available on fallopian tube carcinoma.

Schlüsselwörter

Tubenkarzinom - Stadium III - Adenokarzinom des Eileiters

Key words

Fallopian tube carcinoma - tube cancer - third stage - adeoncarcinoma of the fallopian tube

References

  • 1 Rosenblatt K A, Weiss N S, Schwartz S M. Incidence of malignant fallopian tube tumors.  Gynecol Oncol. 1989;  35 236-239
    CrossrefPubMedGoogle Scholar
  • 2 Roberts J A, Lifshitz S. Primary adenocarcinoma of the fallopian tube.  Gynecol Oncol. 1982;  13 301-308
    CrossrefPubMedGoogle Scholar
  • 3 King A, Seraj I M, Thrasher T, Slater J, Wagner R J. Fallopian tube carcinoma: a clinicopathological study of 17 cases.  Gynecol Oncol. 1989;  33 351-355
    CrossrefPubMedGoogle Scholar
  • 4 Rosen A C, Klein M, Rosen H R, Graf A H, Lahousen M, Reiner A, Vavra N, Auerbach L. Preoperative and postoperative CA‐125 serum levels in primary fallopian tube carcinoma.  Arch Gynecol Obstet. 1994;  255 65-68
    CrossrefPubMedGoogle Scholar
  • 5 Sedlis A. Primary carcinoma of the fallopian tube.  Obstet Gynecol Surv. 1961;  16 209-226
    PubMedGoogle Scholar
  • 6 Johnson G A. Primary malignancy of the fallopian tube: a clinical review of 13 cases.  J Surg Oncol. 1983;  24 304
    PubMedGoogle Scholar
  • 7 Mikami M, Tei C, Kurahashi T, Takehara K, Komiyama S, Suzuki A, Kishikawa T, Fukuiya T. Preoperative diagnosis of fallopian tube cancer by imaging.  Abdom Imaging. 2003;  28 743-747
    CrossrefPubMedGoogle Scholar
  • 8 Nordin A. Primary carcinoma of the fallopian tube: a 20 year literature review.  Obstet Gynecol Surv. 1994;  49 349-361
    PubMedGoogle Scholar
  • 9 Aziz S, Kuperstein G, Rosen B, Cole D, Nedelcu R, McLaughlin J, Narod S A. A genetic epidemiological study of carcinoma of the fallopian tube.  Gynecol Oncol. 2001;  80 341-345
    CrossrefPubMedGoogle Scholar
  • 10 Di Re, Grosso G, Raspagliesi F, Baiocchi G. Fallopian tube cancer: incidence and role of lymphatic spread.  Gynecol Oncol. 1996;  62 199-202
    CrossrefPubMedGoogle Scholar
  • 11 Gaducci A. Current management of fallopian tube carcinoma.  Curr Opin Obstet Gynecol. 2002;  14 27-32
    CrossrefPubMedGoogle Scholar
  • 13 Klein M, Rosen A, Lahousen M, Graf A, Vavra N, Pakish B. Evaluation of adjuvant radiotherapy after surgery for primary carcinoma of the fallopian tube.  Arch Gynecol Obstet. 1994;  255 19-24
    CrossrefPubMedGoogle Scholar
  • 14 Rawlings G, Bush R, Dembo A. Fallopian tube cancer: survival following radiation and chemotherapy. International proceedings. Cairns, Australia; Gynecologic Cancer Society 3rd Biennal Meeting 1991
    Google Scholar
  • 15 Rosen A C, Klein M, Hafner E, Lahousen M, Graf A H, Reiner A. Management and prognosis of primary fallopian tube carcinoma. Austrian Cooperative Study Group for Fallopian Tube Carcinoma.  Gynecol Obstet Invest. 1999;  47 45-51
    CrossrefPubMedGoogle Scholar
  • 16 Muntz H G, Tarraza H M, Granai C O, Fuller Jr A F. Primary adenocarcinoma of the fallopian tube.  Eur J Gynaecol Oncol. 1989;  10 239-249
    PubMedGoogle Scholar
  • 17 Rosen A C, Klein M, Lahousen M. Primary fallopian tube carcinoma in Austria - a retrospective multicenter study.  Br J Cancer. 1993;  68 605-609
    PubMedGoogle Scholar
  • 18 Beckmann M W, von Minckwitz G, Pfisterer J, Schnürch H G, Kreienberg R, Bastert G. Stellungnahme der Arbeitsgemeinschaft Gynäkologische Onkologie (AGO): Nachsorge beim Mammakarzinom und bei gynäkologischen Malignomen - “To follow-up or not to follow-up”.  Geburtsh Frauenheilk. 2003;  63 725-730
    Article in Thieme ConnectPubMedGoogle Scholar
  • 19 Kaum H J, Hohbach S, Wolff F. Virchow-Lymphknoten und Tubenkarzinom.  Geburtsh Frauenheilk. 2001;  61 622-624
    Article in Thieme ConnectPubMedGoogle Scholar

B. Kraemer

Universitaetsfrauenklinik Tuebingen

Calwer Strasse 7

72076 Tuebingen

Germany

Email: bernhardkraemer@gmx.de

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