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Planta Med 2005; 71(8): 792-794
DOI: 10.1055/s-2005-871227
Letter
© Georg Thieme Verlag KG Stuttgart · New York

Diterpene Glycosides from Egletes viscosa

Dongho Lee1 , 4 , Chen Li1 , Tyler N. Graf1 , Jose Schunke Vigo2 , James G. Graham3 , 5 , Fernando Cabieses2 , Norman R. Farnsworth3 , Geoffrey A. Cordell3 , A. Douglas Kinghorn3 , 6 , David J. Kroll1 , Mansukh C. Wani1 , Nicholas H. Oberlies1
  • 1Natural Products Laboratory, Research Triangle Institute, Research Triangle Park, North Carolina, USA
  • 2Instituto Nacional de Medicina Tradicional (INMETRA), Minesterio de Salud, Jesus Maria, Lima, Peru
  • 3Program for Collaborative Research in the Pharmaceutical Sciences and Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois, USA
  • 4Korea Research Institute of Bioscience and Biotechnology, Daejeon, Korea
  • 5Center for Ethnobiology and Natural Products, Florida International University, University Park Campus, Miami, Florida, USA
  • 6Division of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The Ohio State University, Columbus, Ohio, USA
Further Information

Publication History

Received: November 11, 2004

Accepted: February 2, 2005

Publication Date:
11 August 2005 (online)

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Abstract

A phytochemical investigation of the CHCl3-soluble extract of the entire plant of Egletes viscosa (Asteraceae), collected in Peru, afforded two new labdane glycosides, 13-hydroxy-7-oxolabda-8,14-diene 13(R)-O-α-L-arabinopyranoside and 13-hydroxylabda-7,14-diene 13(R)-O-α-L-arabinopyranoside, along with four known compounds. The structures of the new compounds were elucidated by spectroscopic and chemical methods.

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Nicholas H. Oberlies

Natural Products Laboratory

Research Triangle Institute

P.O. Box 12194

Research Triangle Park

North Carolina 27709

USA

Fax: +1-919-541-6499

Email: oberlies@rti.org