Anti-Platelet Aggregating and Anti-Oxidative Activities of 11-O-(4′-O-Methylgalloyl)-bergenin, a New Compound Isolated from Crassula cv. ‘Himaturi’

Abstract

A new compound, 11-O-(4′-O-methylgalloyl)-bergenin was isolated from the MeOH extract of Crassula cv. ‘Himaturi’. The structure of the compound was determined on the basis of chemical and spectroscopic data. It inhibited arachidonic acid-induced platelet aggregation more efficiently than acetylsalicylic acid and showed an anti-oxidative effect (EC₅₀ = 23.9 μM) equivalent to that of L-ascorbic acid or quercetin.

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