Subscribe to RSS
DOI: 10.1055/s-2004-814562
Primary Natural Killer-Cell Lymphoma of the Gastrointestinal Tract
S. J. Lee, M. D.
Department of Internal Medicine
Yong-dong Severance Hospital
Yonsei University College of Medicine
Gangnam-gu
Dogok-dong 146-92
Seoul 135-720
South Korea
Fax: +82-2-34633882
Email: leesj@yumc.yonsei.ac.kr
Publication History
Publication Date:
09 July 2004 (online)
Figure 1 A 70-year-old woman was admitted with lower abdominal pain. An 8-cm mass was palpable in the left lower quadrant of the abdomen. Abdominopelvic computed tomography showed irregular thickening of the small bowel on the left side of the abdominal cavity.
Figure 2 Esophagogastroduodenoscopy demonstrated an ulcerated, infiltrating lesion which occupied 50 % of the lumen in the third part of the duodenum.
Figure 3 Histological examination of the duodenal biopsy revealed a true natural killer-cell lymphoma, with transmural infiltration of large pleomorphic cells. These cells were CD56-positive (Anti-CD56; Santa Cruz Biotechnology Inc., Santa Cruz, California, USA; × 400), but did not express surface CD3 or T-cell lineage.
Figure 4 An ulcerated and excavated mass in a portion of resected jejunum showing multifocal hemorrhage and necrosis. Histologically, this was also revealed to be a true natural killer-cell lymphoma.
S. J. Lee, M. D.
Department of Internal Medicine
Yong-dong Severance Hospital
Yonsei University College of Medicine
Gangnam-gu
Dogok-dong 146-92
Seoul 135-720
South Korea
Fax: +82-2-34633882
Email: leesj@yumc.yonsei.ac.kr
S. J. Lee, M. D.
Department of Internal Medicine
Yong-dong Severance Hospital
Yonsei University College of Medicine
Gangnam-gu
Dogok-dong 146-92
Seoul 135-720
South Korea
Fax: +82-2-34633882
Email: leesj@yumc.yonsei.ac.kr
Figure 1 A 70-year-old woman was admitted with lower abdominal pain. An 8-cm mass was palpable in the left lower quadrant of the abdomen. Abdominopelvic computed tomography showed irregular thickening of the small bowel on the left side of the abdominal cavity.
Figure 2 Esophagogastroduodenoscopy demonstrated an ulcerated, infiltrating lesion which occupied 50 % of the lumen in the third part of the duodenum.
Figure 3 Histological examination of the duodenal biopsy revealed a true natural killer-cell lymphoma, with transmural infiltration of large pleomorphic cells. These cells were CD56-positive (Anti-CD56; Santa Cruz Biotechnology Inc., Santa Cruz, California, USA; × 400), but did not express surface CD3 or T-cell lineage.
Figure 4 An ulcerated and excavated mass in a portion of resected jejunum showing multifocal hemorrhage and necrosis. Histologically, this was also revealed to be a true natural killer-cell lymphoma.