Das Schlaganfall-MRT: Pathophysiologie, Potenzial und Perspektiven

Zusammenfassung

Die Anwendung der Magnetresonanztomographie (MRT) beim Schlaganfall hat sich inzwischen in vielen Zentren durchgesetzt. Diese Methode wird durch die Vielzahl der funktionell-pathophysiologischen Informationen zu einem attraktiven, aber auch komplexen diagnostischen Instrument. Eine unbedingte Voraussetzung für eine rationale Diagnostik bleibt die Kenntnis der pathophysiologischen Korrelate der einzelnen Bestandteile des Untersuchungsprotokolls. Unter Berücksichtigung der Erfahrungen in der klinischen Anwendung sollen in dieser Übersicht einige relevante Elemente der Pathophysiologie des Schlaganfalls dargestellt und die Möglichkeiten des Schlaganfall-MRT bewertet werden. Als weitere Perspektiven für das Schlaganfall-MRT wird das „blood oxygen level dependent” (BOLD)-Imaging sowie die Integration der Informationen aus den verschiedenen Sequenzen in Prädiktionskarten für das Gewebeschicksal diskutiert.

Abstract (noch nicht bearbeitet)

Magnetic resonance imaging (MRI) is increasingly utilized as the primary imaging modality in major stroke centers. The ability to depict several aspects of individual pathophysiology makes the use of MRI in stroke both attractive and complex. Profound knowledge of the pathophysiology of the imaging findings is crucial for a rational diagnostic workup. The pathophysiology of MRI in stroke will be reviewed considering recent experiences in clinical application, and the potential of stroke MRI will be assessed. Further perspectives like application of “blood oxygen level dependent” (BOLD) and the use of multiparametric prediction maps will be discussed.

Key words

Magnetic resonance imaging - diffusion - perfusion - stroke - thrombolysis

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