Endoscopy 2003; 35(5): 464
DOI: 10.1055/s-2003-38761
Images in Focus

© Georg Thieme Verlag Stuttgart · New York

Novel Endosonographic Findings in Cronkhite-Canada Syndrome

E.  M.  Ward1 , H.  C.  Wolfsen1 , M.  Raimondo1
  • 1Division of Gastroenterology and Hepatology, Mayo Clinic, Jacksonville, Florida, USA
Further Information

H. C. Wolfsen, M.D.

Division of Gastroenterology and HepatologyMayo Clinic

4500 San Pablo RoadJacksonville, FL 32224USA

Fax: + 1-904-953-7260

Email: pdt@mayo.edu

Publication History

Publication Date:
17 April 2003 (online)

Table of Contents
    Zoom Image

    Figure 1 The CT scan shows markedly thickened gastric walls in a patient with Cronkhite-Canada syndrome.

    Zoom Image

    Figure 2 Since there has been at least one report of gastric adenocarcinoma occurring in Cronkhite-Canada syndrome, endosonography was performed to further investigate the gastric wall thickening. This study revealed distinctive submucosal cystic structures. Fine-needle aspiration of the largest cyst was performed; cytology was negative. The significance of these submucosal cysts is not known.

    Zoom Image

    Figure 3 Endoscopic appearance of the distal stomach, showing innumerable microcystic polyps.

    H. C. Wolfsen, M.D.

    Division of Gastroenterology and HepatologyMayo Clinic

    4500 San Pablo RoadJacksonville, FL 32224USA

    Fax: + 1-904-953-7260

    Email: pdt@mayo.edu

    H. C. Wolfsen, M.D.

    Division of Gastroenterology and HepatologyMayo Clinic

    4500 San Pablo RoadJacksonville, FL 32224USA

    Fax: + 1-904-953-7260

    Email: pdt@mayo.edu

    Zoom Image

    Figure 1 The CT scan shows markedly thickened gastric walls in a patient with Cronkhite-Canada syndrome.

    Zoom Image

    Figure 2 Since there has been at least one report of gastric adenocarcinoma occurring in Cronkhite-Canada syndrome, endosonography was performed to further investigate the gastric wall thickening. This study revealed distinctive submucosal cystic structures. Fine-needle aspiration of the largest cyst was performed; cytology was negative. The significance of these submucosal cysts is not known.

    Zoom Image

    Figure 3 Endoscopic appearance of the distal stomach, showing innumerable microcystic polyps.