Planta Med 2002; 68(11): 995-998
DOI: 10.1055/s-2002-35657
Original Paper
Pharmacology
© Georg Thieme Verlag Stuttgart · New York

Polyphenols from the Heartwood of Cercidiphyllum japonicum and their Effects on Proliferation of Mouse Hair Epithelial Cells

Keisuke Towatari1 , Kiyo Yoshida1 , Nobuhiro Mori1 , Kuniyoshi Shimizu1 , Ryuichiro Kondo1 , Kokki Sakai1
  • 1Department of Forest and Forest Products Sciences, Faculty of Agriculture, Kyushu University, Fukuoka, Japan
Further Information

Publication History

Received: February 8, 2002

Accepted: June 1, 2002

Publication Date:
26 November 2002 (online)

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Abstract

The methanol extract of heartwood of Cercidiphyllum japonicum (Cercidiphyllaceae) stimulated proliferation of mouse hair epithelial cells, similar to minoxidil and procyanidin B-2. (+)-Taxifolin (2), quercetin (3), myricetin (4), (+)-dihydromyricetin (5) and gallic acid (6) were isolated from C. japonicum and showed significant proliferative activities on the hair epithelial cells.

References

Prof. Ryuichiro Kondo

Laboratory of Systematic Forest and Forest Products Science

Department of Forestry and Forest Products Sciences

Faculty of Agriculture

Kyushu University

6-10-1 Hakozaki

Higashi-ku

Fukuoka, 812-8581

Japan

Phone: /Fax: +81-92-642-2811

Email: kondo@brs.kyushu-u.ac.jp