Minim Invasive Neurosurg 2001; 44(2): 70-73
DOI: 10.1055/s-2001-16002
ORIGINAL PAPER
Georg Thieme Verlag Stuttgart · New York

Endoscopic Surgery for Pineal Region Tumors

M. Gangemi, F. Maiuri, G. Colella, S. Buonamassa
  • Department of Neurosurgery, University Federico II, Naples, Italy
Further Information

Publication History

Publication Date:
31 December 2001 (online)

Endoscopic surgery may play an important role in most patients with pineal region tumors. We report our experience with 5 patients treated by a burr hole endoscopic technique. The procedure included in all cases third ventriculostomy for the correction of hydrocephalus, CSF sample for cytology and tumor markers, and tumor biopsy for histological diagnosis. Endoscopic biopsies showed a pineocytoma in two cases, a germinoma in 2 and a low-grade astrocytoma in one. We agree that endoscopic surgery may allow us to select cases requiring a microsurgical approach (medium-sized or large non-germ-cell tumors) from cases to be treated only by irradiation and chemotherapy (germinomas and other non-germ-cell tumors). Then, in some patients with pineal region tumors the endoscopic procedure remains the only surgical treatment. When a direct microsurgical approach is indicated, it may be performed in a non-emergency situation and after correction of the hydrocephalus by endoscopic third ventriculostomy.

References

  • 1 Stein B M, Bruce J N. Surgical management of pineal region. In: Selma WS (ed). Clinical Neurosurgery: Proceedings of the Congress of Neurological Surgeons Baltimore: Williams & Wilkins 1992 vol. 39: 509-532
  • 2 Berger M S, Baumeister B, Geyer J R, Milstein J, Kanev P, LeRoux P D. The risks of metastases from shunting in children with primary central nervous system tumors.  J Neurosurg. 1991;  74 872-877
  • 3 Pallini R, Bozzini V, Scerrati M, Zuppi C, Zappacosta B, Rossi G F. Bone metastasis associated with shunt-related peritoneal deposits from a pineal germinoma. Case report and review of the literature.  Acta Neurochir. 1991;  109 78-83
  • 4 Ferrer E, Santamarta D, Garcia-Fructuoso G, Coral L, Rumia J. Neuroendoscopic management of pineal region tumors.  Acta Neurochir. 1997;  139 12-20
  • 5 Robinson S, Cohen A R. The role of neuroendoscopy in the treatment of pineal region tumors.  Surg Neurol. 1997;  40 360-365
  • 6 Veto F, Horvatz Z, Docai T. Biportal endoscopic management of third ventricle tumors in patients with occlusive hydrocephalus: technical note.  Neurosurgery. 1997;  40 871-875
  • 7 Gaab M R, Schroeder H WS. Endoscopy of intraventricular lesions. In: King W, Frazee J, De Salles A (eds): Endoscopy of the central and Peripheral Nervous System New York - Stuttgart: Thieme 1998 chap 7: 68-77
  • 8 Dallolio V, Monolo L, Lunghi A, Severi P. Pineal region masses: the role of neuroendoscopy.  Minim Invas Neurosurg. 1999;  42 103
  • 9 Gangemi M, Maiuri F, de Divitiis E. Neuroendoscopia: Diagnostica per immagini, tecniche e risultati.  Napoli: Idelson. 2000;  170-173
  • 10 Stein B M. The infratentorial supracerebellar approach to pineal lesions.  J Neurosurg. 1971;  35 197-202
  • 11 Poppen J L. The right occipital approach to a pinealoma.  J Neurosurg. 1996;  25 706-709
  • 12 Sawaya R, Hawley D K, Tobler W D. et al .Pineal and third ventricle tumors. In: Youmans JR (ed): Neurological Surgery Philadelphia: Saunders 1990: 3171-3203
  • 13 Sano K. Treatment of tumors of the pineal and posterior third ventricular region. In: Samii M (ed): Surgery in and around the Brainstem and the Third Ventricle Berlin: Springer 1986
  • 14 Cohen A R. Comment on Ruge JR, Johnson RF, Bauer J: Burr hole neuroendoscopic fenestration of quadrigeminal arachnoid cyst: technical case report.  Neurosurgery. 1996;  38 873
  • 15 Perneczky A. Comment on Ruge JR, Johnson RF, Bauer J: Burr hole neuroendoscopic fenestration of quadrigeminal arachnoid cyst: technical case report.  Neurosurgery. 1996;  38 873
  • 16 Ostertag C B. Comment on Robinson S, Cohen AR: The role of neuroendoscopy in the treatment of pineal region tumors.  Surg Neurol. 1997;  48 365-366
  • 17 Apuzzo M JL, Chandrasoma P T, Zelman V. et al . Computed tomographic guidance stereotaxis in the management of lesions of the third ventricular region.  Neurosurgery. 1984;  35 502-508
  • 18 Pecker J, Scarabin J M, Vallee B. Treatment of tumours in the pineal region: value of stereotactic biopsy.  Surg Neurol. 1979;  12 341
  • 19 Ellenbogen R G, Moores L E. Endoscopic management of a pineal and suprasellar germinoma with associated hydrocephalus: technical case report.  Minim Invasiv Neurosurg. 1997;  40 13-16

Corresponding Author

Prof M Gangemi

Dipartimento di Scienze Neurologiche
Università Federico II

Via Sergio Pansini 5
80131 Naples
Italy

Phone: Phone and Fax: +39-081-7462576

    >