Semin Reprod Med 2001; 19(2): 167-174
DOI: 10.1055/s-2001-15396
Copyright © 2001 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA. Tel.: +1(212) 584-4662

Differential Hybridization and Other Strategies to Identify Novel Ovarian Genes

Adriano B. Tavares1 2 , Michael S. Esplin1 , Eli Y. Adashi1
  • 1Division of Reproductive Sciences, Department of Obstetrics and Gynecology, University of Utah Health Sciences Center, Salt Lake City, Utah and
  • 2Department of Obstetrics and Gynecology, School of Medicine of Ribeirao Preto, University of Sao Paulo, Sao Paulo, Brazil
Further Information

Publication History

Publication Date:
31 December 2001 (online)

ABSTRACT

Approaches to define patterns of gene expression have applications in a wide range of biological systems. The completion of the human genome project establishes a unique opportunity to understand the molecular control of different biological events through functional analysis. However, the huge database that currently exists will demand the utilization of high-throughput techniques for the assessment of multiple DNA sequences in a rapid and efficient manner. By determining genes with differential expression, it may be possible to decipher the mechanisms that underlie the control of different physiological pathways, which, in turn, may define future strategies to manage them. Although there exist a vast number of tools to screen genes for differential expression, we briefly examine here only some of those with regard to their advantages and disadvantages.

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