Gastric Cancer Presenting with Extremely Rapid Growth: Unprecedented Morphologic Change in a Short Time and Endoscopic Estimation of its Doubling Time

T. Nakajima; H. Konishi; Y. Tatsumi; Y. Sakamoto; Y. Yamane; S. Misawa; S. Toyama; T. Ochiai; K. Kashima; E. Konishi; Y. Tsuchihashi

doi:10.1055/s-2000-9616

Endoscopy 2000; 32(12): 994-997
DOI: 10.1055/s-2000-9616

Case Report

Gastric Cancer Presenting with Extremely Rapid Growth: Unprecedented Morphologic Change in a Short Time and Endoscopic Estimation of its Doubling Time

T. Nakajima ^{1, 2} , H. Konishi ^{1, 2} , Y. Tatsumi ^{1, 2} , Y. Sakamoto ^{1, 2} , Y. Yamane ^{1, 2} , S. Misawa ^{1, 2} , S. Toyama ^{1, 2} , T. Ochiai ³ , K. Kashima ² , E. Konishi ⁴ , Y. Tsuchihashi ⁴

¹ Department of Gastroenterology, Kyoto Prefectural Yosano-umi Hospital, Kyoto, Japan
² Department of Surgery, Kyoto Prefectural Yosano-umi Hospital, Kyoto, Japan
³ Third Department of Internal Medicine, Kyoto Prefectural Yosano-umi Hospital, Kyoto, Japan
⁴ Hospital Department of Pathology, Kyoto Prefectural University of Medicine, Kyoto, Japan

Abstract

We encountered a case of gastric cancer that was initially detected as a deep hemorrhagic ulcer without surrounding irregular elevation, followed by rapid protrusion in less than 1 month. Using endoscopic images in the follow-up study, we estimated the doubling time (DT) of this unusual tumor as 9.2 days. Since the doubling time of gastric cancer is generally fairly long due to exfoliation of many cancer cells into the gastric lumen, this cancer presented with extremely rapid growth. Besides, this case reinforces that follow-up study is important in terms of clinical management of ulcerative lesions.

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References

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Tomoki Nakajima, M.D.

Department of Gastroenterology Kyoto Prefectural Yosano-umi Hospital

Otokoyama Iwataki-cho

Yosa-gun

Kyoto Prefecture 629- 2261 Japan

Fax: Fax:+ 81-772-46-2728

Email: E-mail:tomnaka@silver.ocn.ne.jp