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Semin Reprod Med 2000; 18(2): 195-204
DOI: 10.1055/s-2000-12558
Copyright © 2000 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA. Tel.: +1(212) 584-4662

Regulation of Ionic Homeostasis by Mammalian Embryos

Michelle Lane, David K. Gardner
  • Colorado Center for Reproductive Medicine, Englewood, Colorado
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Publication History

Publication Date:
31 December 2000 (online)

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ABSTRACT

Control and regulation of cellular homeostasis are essential for normal embryo development and maintenance of viability. By understanding the role of ionic homeostasis in normal cell development and homeostatic control by the developing embryo, it is possible to develop culture systems that minimize cellular stress and therefore maintain embryo viability. This article discusses the regulation of intracellular levels of protons (pHi), calcium, magnesium, and phosphate in mammalian embryos.

KEYWORD

calcium - magnesium - phosphate - embryo development

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