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DOI: 10.1055/s-0045-1814139
Flap Monitoring and Postoperative ICU Care after Microsurgical Head and Neck Reconstruction
Authors
Abstract
Free tissue transfer has become the gold standard for reconstructing complex head and neck defects, achieving success rates exceeding 95% in experienced centers. Despite these advances, vascular compromise remains the leading cause of flap failure, most commonly occurring within the first 24 to 72 hours postoperatively. Early detection of arterial or venous thrombosis is therefore critical to maximize flap salvage and optimize patient outcomes. Conventional clinical monitoring, including assessing flap color, temperature, capillary refill, tissue turgor, and bleeding on pinprick, remains the cornerstone of postoperative surveillance due to its simplicity, noninvasiveness, and universal applicability. However, its accuracy depends heavily on clinical experience and is limited in cases such as buried or intraoral flaps where direct observation is restricted. To improve diagnostic sensitivity and objectivity, various adjunctive technologies have been introduced, including handheld and implantable Doppler ultrasonography, laser Doppler flowmetry, thermography, and near-infrared (indocyanine green) angiography. These modalities can provide quantitative or continuous perfusion data, facilitating earlier recognition of vascular compromise. Nonetheless, each technique carries limitations related to cost, invasiveness, and susceptibility to artifacts, and no single method has proven superior to clinical evaluation alone. Effective monitoring requires structured protocols, multidisciplinary coordination, and prompt surgical re-exploration when perfusion deficits are suspected. Integration of multimodal strategies tailored to flap type and patients offer the best balance between sensitivity and practicality. This paper aims to standardize monitoring algorithms, evaluate cost-effectiveness, and explore novel technologies such as artificial intelligence–assisted systems to further enhance early detection, improve flap salvage rates, and optimize reconstructive outcomes.
Declaration of GenAI Use
During the writing process of this paper, the author used free ChatGPT tool in order to assist the grammar and language fluency. The authors reviewed and edited the text and take full responsibility for the content of the paper.
Publication History
Article published online:
18 December 2025
© 2025. Thieme. All rights reserved.
Thieme Medical Publishers, Inc.
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References
- 1 Rogoń I, Rogoń A, Kaczmarek M. et al. Flap monitoring techniques: a review. J Clin Med 2024; 13 (18) 5467
- 2 Wang W, Ong A, Vincent AG, Shokri T, Scott B, Ducic Y. Flap failure and salvage in head and neck reconstruction. Semin Plast Surg 2020; 34 (04) 314-320
- 3 Patel UA, Hernandez D, Shnayder Y. et al. Free flap reconstruction monitoring techniques and frequency in the era of restricted resident work hours. JAMA Otolaryngol Head Neck Surg 2017; 143 (08) 803-809
- 4 Shen AY, Lonie S, Lim K, Farthing H, Hunter-Smith DJ, Rozen WM. Free flap monitoring, salvage, and failure timing: a systematic review. J Reconstr Microsurg 2021; 37 (03) 300-308
- 5 Leader R. Flap monitoring in head & neck reconstructive surgery—a review of the literature. Adv Oral Maxillofac Surg 2023; 12: 100463
- 6 Knoedler S, Hoch CC, Huelsboemer L. et al. Postoperative free flap monitoring in reconstructive surgery—man or machine?. Front Surg 2023; 10: 1130566
- 7 Mao C, Yu GY, Peng X, Guo CB, Huang MX. [Postoperative vessel thrombosis and its management after free flap transfers in head and neck region] [in Chinese]. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2005; 40 (06) 415-418
- 8 Kohlert S, Quimby AE, Saman M, Ducic Y. Postoperative free-flap monitoring techniques. Semin Plast Surg 2019; 33 (01) 13-16
- 9 Dionyssopoulos A, Odobescu A, Foroughi Y. et al. Monitoring buried jejunum free flaps with a sentinel: a retrospective study of 20 cases. Laryngoscope 2012; 122 (03) 519-522
- 10 Tan NC, Shih HS, Chen CC, Chen YC, Lin PY, Kuo YR. Distal skin paddle as a monitor for buried anterolateral thigh flap in pharyngoesophageal reconstruction. Oral Oncol 2012; 48 (03) 249-252
- 11 Kudpaje A, Thankappan K, Rajan RP. et al. Outcomes of re-exploration procedures after head and neck free flap reconstruction. Indian J Surg Oncol 2021; 12 (03) 530-537
- 12 Odorico SK, Reuter Muñoz K, JNicksic P. et al. Surgical and demographic predictors of free flap salvage after takeback: a systematic review. Microsurgery 2023; 43 (01) 78-88
- 13 Yalamanchi P, Peddireddy NS, McMichael B. et al. Team-based surgical approach to head and neck microvascular free flap reconstruction. JAMA Otolaryngol Head Neck Surg 2023; 149 (11) 1021-1026
- 14 Krijgh DD, van Straeten MME, Mureau MAM. et al. Postoperative care in microvascular free flap reconstruction of the lower extremity: a systematic review. Orthoplastic Surg 2020; 1–2 (0C:) 21-26
- 15 Lacey H, Kanakopoulos D, Hussein S, Moyasser O, Ward J, King ICC. Adjunctive technologies in postoperative free-flap monitoring: a systematic review. J Plast Reconstr Aesthet Surg 2023; 87: 147-155
- 16 Salgado CJ, Chim H, Schoenoff S, Mardini S. Postoperative care and monitoring of the reconstructed head and neck patient. Semin Plast Surg 2010; 24 (03) 281-287
- 17 Chubb D, Rozen WM, Whitaker IS, Acosta R, Grinsell D, Ashton MW. The efficacy of clinical assessment in the postoperative monitoring of free flaps: a review of 1140 consecutive cases. Plast Reconstr Surg 2010; 125 (04) 1157-1166
- 18 Pafitanis G, Chen HC. The pinprick test: key considerations in execution of skin flap perfusion testing. Plast Reconstr Surg Glob Open 2019; 7 (09) e2370
- 19 Kwasnicki RM, Noakes AJ, Banhidy N, Hettiaratchy S. Quantifying the limitations of clinical and technology-based flap monitoring strategies using a systematic thematic analysis. Plast Reconstr Surg Glob Open 2021; 9 (07) e3663
- 20 Cevallos PC, Najafali D, Johnstone TM. et al. Detecting flap compromise: an updated review of techniques to monitor microsurgical flaps post-operatively in breast reconstruction. Plast Aesthet Res 2023; 10: 30
- 21 Hallock GG. Acoustic Doppler sonography, color duplex ultrasound, and laser Doppler flowmetry as tools for successful autologous breast reconstruction. Clin Plast Surg 2011; 38 (02) 203-211
- 22 Yamada A, Hori A, Eguchi T. Use of handheld ultrasound for flap monitoring after free jejunal transfer. J Plast Reconstr Surg 2023; 3 (01) 39-42
- 23 Chang TY, Lee YC, Lin YC. et al. Implantable Doppler probes for postoperatively monitoring free flaps: efficacy. A systematic review and meta-analysis. Plast Reconstr Surg Glob Open 2016; 4 (11) e1099
- 24 Poder TG, Fortier PH. Implantable Doppler in monitoring free flaps: a cost-effectiveness analysis based on a systematic review of the literature. Eur Ann Otorhinolaryngol Head Neck Dis 2013; 130 (02) 79-85
- 25 Smit JM, Klein S, de Jong EH, Zeebregts CJ, de Bock GH, Werker PM. Value of the implantable doppler system in free flap monitoring. J Plast Reconstr Aesthet Surg 2012; 65 (09) 1276-1277
- 26 Chim H, Nichols DS, Chopan M. Ultrasound for perforator mapping and flap design in the hand and upper extremity. J Hand Surg Am 2023; 48 (06) 595-601
- 27 Cowan R, Mann G, Salibian AA. Ultrasound in microsurgery: current applications and new frontiers. J Clin Med 2024; 13 (12) 3412
- 28 Kodama H, Ishida K, Hirayama H. et al. Correlation between laser Doppler flowmetry metrics and continuous blood pressure in free flap monitoring. J Plast Reconstr Aesthet Surg 2024; 96: 196-198
- 29 Kodama H, Ishida K, Hirayama H. et al. The future of free flap monitoring by laser continuous doppler flowmetry: a prospective assessment in consecutive 71 patients. JPRAS Open 2024; 43: 140-152
- 30 Mücke T, Hapfelmeier A, Schmidt LH. et al. A comparative analysis using flowmeter, laser-Doppler |spectrophotometry, and indocyanine green-videoangiography for detection of vascular stenosis in free flaps. Sci Rep 2020; 10 (01) 939
- 31 Salvatori P, Paradisi S, Zani A. Free flaps monitoring by Laser-Doppler Flowmetry in head and neck surgery. Acta Otorhinolaryngol Ital 2022; 42 (05) 427-433
- 32 Lu Y, Sun N, Wu P, Zhou G, Peng L, Tang J. The application of infrared thermography technology in flap: a perspective from bibliometric and visual analysis. Int Wound J 2023; 20 (10) 4308-4327
- 33 Singla P, Dixit PK, Kala PC. et al. Free flap monitoring using infrared thermography: an objective adjunct to clinical monitoring. Indian J Plast Surg 2024; 57 (03) 179-183
- 34 Hallock GG. Dynamic infrared thermography and smartphone thermal imaging as an adjunct for preoperative, intraoperative, and postoperative perforator free flap monitoring. Plast Aesthet Res 2019; 6: 29
- 35 Hennessy O, Potter SM. Use of infrared thermography for the assessment of free flap perforators in autologous breast reconstruction: a systematic review. JPRAS Open 2019; 23: 60-70
- 36 Bian HZ, Pek CH, Hwee J. Current evidence on the use of near-infrared spectroscopy for postoperative free flap monitoring: a systematic review. Chin J Plast Reconstr Surg 2022; 4 (04) 194-202
- 37 Krishnan KG, Schackert G, Steinmeier R. The role of near-infrared angiography in the assessment of post-operative venous congestion in random pattern, pedicled island and free flaps. Br J Plast Surg 2005; 58 (03) 330-338
- 38 Tange FP, Verduijn PS, Sibinga Mulder BG. et al. Near-infrared fluorescence angiography with indocyanine green for perfusion assessment of DIEP and msTRAM flaps: a Dutch multicenter randomized controlled trial. Contemp Clin Trials Commun 2023; 33: 101128
- 39 Birkenfeld F, Naujokat H, Helmers AK, Purcz N, Möller B, Wiltfang J. Microdialysis in postoperative monitoring of microvascular free flaps: experiences with a decision algorithm. J Craniomaxillofac Surg 2019; 47 (08) 1306-1309
- 40 Jyränki J, Suominen S, Vuola J, Bäck L. Microdialysis in clinical practice: monitoring intraoral free flaps. Ann Plast Surg 2006; 56 (04) 387-393
- 41 Halani SH, Hembd AS, Li X. et al. Flap monitoring using transcutaneous oxygen or carbon dioxide measurements. J Hand Microsurg 2020; 14 (01) 10-18
- 42 Zingaretti N, Di Filippo J, Robiony M. et al. Free flap monitoring of tissue oxygen saturation: a new device in oral reconstruction. Oral Oncol 2024; 149: 106693
- 43 Kim J, Lee SM, Kim DE. et al. Development of an automated free flap monitoring system based on artificial intelligence. JAMA Netw Open 2024; 7 (07) e2424299
- 44 Kim H, Kim D, Bai J. Machine learning approaches overcome imbalanced clinical data for intraoral free flap monitoring. Sci Rep 2025; 15 (01) 34849
- 45 Ye Z, Sun D, Gary SE. Revolutionizing postoperative free flap monitoring—the promise of AI to improve health outcomes. JAMA Netw Open 2024; 7 (07) e2424297
