CORRELATION BETWEEN THE PREVALENCE OF COLORECTAL POLYPS IN PATIENTS WITH AND WITHOUT A FAMILY HISTORY OF COLORECTAL CANCER

Objectives To assess the prevalence of polyps in asymptomatic patients undergoing colonoscopy for screening, comparing patients with a family history of colorectal cancer to those without a family history.

Methods A cross-sectional study was conducted on a group of individuals who underwent colonoscopy between January 2019 and April 2024. Patients were divided into two groups: Group I (without a family history of colorectal cancer) and Group II (with a family history in first-degree relatives). Demographic characteristics, colonoscopy findings, presence, location, and histological type of polyps were evaluated and compared between the two groups.

Results A total of 1,497 patients were evaluated, with 1,367 in Group I and 130 in Group II. Polypoid lesions were found in 550 patients (36.7%), with 506 (37%) in Group I and 44 (33.8%) in Group II. In Group I, 243 (48%) had hyperplastic polyps, 188 (37%) had adenomatous polyps (120 tubular with low-grade dysplasia, 40 tubular with high-grade dysplasia, 28 tubulovillous with high-grade dysplasia), and 75 (15%) had inflammatory polyps. In Group II, 22 (50%) had hyperplastic polyps, 20 (45.4%) had adenomatous polyps (12 tubular with low-grade dysplasia, 6 tubular with low-grade dysplasia, 4 tubulovillous with high-grade dysplasia), and 2 (4.6%) had inflammatory polyps. There was no statistically significant difference between the groups (p=0.83). The prevalence of adenomas was similar in both groups (Group I = 188/37% vs Group II = 20/45.4%) (p=0.83). The distribution of patients with polyps was similar in terms of sex, with polyps found in 339 (40%) female patients and 167 (31%) male patients in Group I (p=1.00), and in 33 (37%) female patients and 11 (21%) male patients in Group II (p=1.00).

Conclusion In this initial study, no correlation was found between the prevalence of polyps and a family history of colorectal cancer.

Die Autoren geben an, dass kein Interessenkonflikt besteht.

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Artikel online veröffentlicht:
25. April 2025